OBJECTIVE: The goal was to determine whether the quality of general movements (GMs) for preterm children had predictive value for cognitive development at school age. METHODS: In this prospective cohort study, 60 preterm infants (gestational age, median: 30.0 weeks [range: 25-33 weeks]; birth weight, median: 1130 g [range: 595-1800 g]) without cerebral palsy were studied. The quality of GMs was assessed prospectively as normal or abnormal, from video recordings that were made at regular intervals until 17 weeks after term. At 7 to 11 years, intelligence was tested by using the Wechsler Intelligence Scale for Children III, Dutch version. Total IQ (TIQ), verbal IQ (VIQ), and performance IQ (PIQ) scores were calculated. RESULTS: The median TIQ was 93 (range: 67-113), VIQ 96 (range: 68-117), and PIQ 92 (range: 65-119). Fifteen children (25%) had low TIQ scores (<85). When the quality of GMs normalized before 8 weeks after term, TIQ, VIQ, and PIQ scores were in the normal range. Consistently abnormal GMs to 8 weeks after term were associated with lower TIQ, VIQ, and PIQ scores. With correction for male gender and the educational levels of the parents, the likelihood ratio of consistently abnormal GMs for a low TIQ was 4.9 (95% confidence interval: 1.3-17.6). The model explained 22.4% of the variance. CONCLUSIONS: The quality of GMs during the early postterm period is a marker for intelligence at school age. Abnormal GMs during the early postterm period may reflect injury or developmental disruptions of brain areas involved in cognitive development.
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机译：目的：目的是确定早产儿的一般运动（GM）的质量是否对学龄期的认知发展具有预测价值。方法：在这项前瞻性队列研究中，研究了60名没有脑瘫的早产儿（胎龄，中位数：30.0周[范围：25-33周];出生体重，中位数：1130 g [范围：595-1800 g]）。从定期录制直到足月17周后的录像中，对GM的质量进行了前瞻性评估，以评估其是否正常。在7至11岁时，使用荷兰语的韦氏儿童智力测验III对智力进行了测试。计算总智商（TIQ），口头智商（VIQ）和表现智商（PIQ）分数。结果：TIQ中位数为93（范围：67-113），VIQ 96（范围：68-117）和PIQ 92（范围：65-119）。 15名儿童（25％）的TIQ分数较低（<85）。当分娩后8周前GM的质量恢复正常时，TIQ，VIQ和PIQ得分在正常范围内。足月后至第8周的持续异常GM与较低的TIQ，VIQ和PIQ得分相关。在校正了男性性别和父母的教育程度之后，TIQ较低时持续异常的GM的似然比为4.9（95％置信区间：1.3-17.6）。该模型解释了22.4％的方差。结论：早产期GMs的质量是学龄儿童智力的标志。早期早期的GM异常可能反映出与认知发育有关的大脑区域的损伤或发育障碍。
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