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首页> 外文期刊>Pediatric diabetes. >The incidence of type 1 diabetes in Republic of Srpska (Bosnia and Herzegovina) and Slovenia in the period 1998-2010
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The incidence of type 1 diabetes in Republic of Srpska (Bosnia and Herzegovina) and Slovenia in the period 1998-2010

机译：1998-2010年期间，斯普斯卡共和国（波斯尼亚和黑塞哥维那）和斯洛文尼亚1型糖尿病的发病率

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Objective: To establish and compare the incidence and trends of type 1 diabetes mellitus (T1DM) in Republic of Srpska and Slovenia in age group 0-18 yr from 1998 to 2010. Methods: The subjects (413 newly diagnosed T1DM patients in the Republic of Srpska and 664 in Slovenia) were grouped into the age groups: 0-4, 5-9, 10-14, and 15-18 yr. Confidence intervals (CI) for crude incidence rates were estimated assuming numbers of cases were counts from the Poisson distribution. Gender and age-specific standardization was done according to the EURODIAB criteria. Statistical analysis used Poisson-regression models to analyze difference rate between countries and to investigate the incidence trend. Results: Case ascertainment was estimated to be 99.95% for the Republic of Srpska and 100% for Slovenia by using the capture-recapture method. The standardized incidence of T1DM for age group 0-18 yr in the Republic of Srpska was 7.5/100 000/yr (95% CI: 6.8-8.3). For the same period and the same age group incidence in Slovenia was 12.5/100 000/yr (95% CI: 11.5-13.5). Annual increase in the incidence in the Republic of Srpska was 2.3% (95% CI: -0.3 to 5.0%), whereas in Slovenia 4.3% (95% CI: 2.2-6.5%). Conclusion: The incidence for age group 0-18 yr standardized to the world population is remarkably higher in Slovenia than in the Republic of Srpska. Further follow-up and investigations are needed to explain the high difference in incidence of T1DM between the two geographically related countries.
机译：目的：建立并比较1998年至2010年在0-18岁年龄段的斯普斯卡共和国和斯洛文尼亚共和国1型糖尿病（T1DM）的发病率和趋势。方法：受试者（共413名在共和国新诊断为T1DM的患者）斯洛文尼亚的Srpska和664）分为0-4、5-9、10-14和15-18岁年龄段。假设病例数是根据Poisson分布计算得出的，则估计粗略发病率的置信区间（CI）。根据EURODIAB标准进行了性别和特定年龄的标准化。统计分析使用泊松回归模型分析国家之间的差异率并调查发病率趋势。结果：使用捕获-再捕获方法，斯普斯卡共和国的病例确诊率估计为99.95％，斯洛文尼亚为100％。斯普斯卡共和国0-18岁年龄组的T1DM标准化发病率为7.5 / 100 000 /年（95％CI：6.8-8.3）。在同一时期和同一年龄段，斯洛文尼亚的发病率为12.5 / 100 000 /年（95％CI：11.5-13.5）。斯普斯卡共和国的发病率年增长率为2.3％（95％CI：-0.3至5.0％），而斯洛文尼亚为4.3％（95％CI：2.2-6.5％）。结论：标准化为世界人口的0-18岁年龄组的发病率在斯洛文尼亚比在斯普斯卡共和国高得多。需要进一步的随访和调查，以解释两个地理相关国家之间的T1DM发病率差异很大。

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