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首页> 外文期刊>Pediatric diabetes. >Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls
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Hormonal response during physical exercise of different intensities in adolescents with type 1 diabetes and healthy controls

机译：1型糖尿病青少年和健康对照组不同强度体育锻炼过程中的激素反应

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Background Physical activity is a critical component in the care of diabetes. Although it offers health benefits it presents challenges. Objective To investigate differences between adolescent boys and girls with type 1 diabetes and healthy controls in terms of maximal work capacity (VO2 max) and hormonal response to physical exercise of different intensities. Subjects Twelve individuals (six boys and six girls; age 1419 yr, pubertal stage 45) with type 1 diabetes (duration, 6.3 +/- 4.4 yr; hemoglobin A1c, 63 +/- 10 mmol/mol) were compared with 12 healthy controls matched for age, sex, pubertal stage, body mass index standard deviation score, and amount of regular physical activity. Methods During consecutive days, three different workloads; maximal, endurance, and interval, were performed on an Ergometer cycle. During the tests, levels of lactate, glucose, insulin, and regulatory hormones [glucagon, cortisol, growth hormone (GH), adrenaline, and noradrenaline] were measured in blood. Subcutaneous glucose was measured continuously. Results VO2 max did not differ between the groups, diabetes 49.8 +/- 9.9 vs. control 50.7 +/- 12.0 mL/min/kg. Hormonal responses did not differ between the groups except for mean peak GH level during the interval test, diabetes 63.2 +/- 27.0 vs. control 33.8 +/- 20.9 mU/L, p < 0.05. Conclusions Physical capacity and hormonal regulation of blood glucose in connection with physical exercise of different intensities did not differ between adolescents with diabetes and healthy controls. Thus, adolescents with type 1 diabetes can participate in physical activity on the same terms as healthy peers.
机译：背景运动是糖尿病护理中的关键组成部分。尽管它具有健康益处，但也带来了挑战。目的研究1型糖尿病青春期男孩和女孩与健康对照者在最大强度（VO2 max）和不同强度体育锻炼荷尔蒙反应方面的差异。将十二个患有1型糖尿病（持续时间6.3 +/- 4.4岁;血红蛋白A1c，63 +/- 10 mmol / mol）的个体（六个男孩和六个女孩;年龄1419岁，青春期45岁）与12个健康对照组进行比较与年龄，性别，青春期，体重指数标准差评分和有规律的体育锻炼量匹配。方法在连续的几天中，三种不同的工作量;最大，耐力和间隔是在测力计周期上进行的。在测试过程中，测量了血液中的乳酸，葡萄糖，胰岛素和调节激素（胰高血糖素，皮质醇，生长激素（GH），肾上腺素和去甲肾上腺素）的水平。连续测量皮下葡萄糖。结果两组之间的最大摄氧量无差异，糖尿病为49.8 +/- 9.9，而对照组为50.7 +/- 12.0 mL / min / kg。两组间的激素反应无差异，除了间隔试验中的平均GH峰值水平，糖尿病为63.2 +/- 27.0，而对照组为33.8 +/- 20.9mU / L，p <0.05。结论糖尿病青少年和健康对照者在不同强度的体育锻炼中的身体机能和血糖激素调节没有差异。因此，患有1型糖尿病的青少年可以与健康同龄人一样参加体育锻炼。

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