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首页> 外文期刊>Pediatric Hematology and Oncology >Effects of transfusion in anemia of prematurity.
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Effects of transfusion in anemia of prematurity.

机译:输血对早产儿贫血的影响。

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The authors aimed to test the hypothesis that blood transfusions depress hematopoiesis in healthy infants with anemia of prematurity (AOP). They also set out to find markers that predict recovery from AOP. Thirty-nine premature babies underwent weekly and post-transfusion measurements of hemoglobin concentrations, reticulocyte counts (RCC), and erythropoietin levels (EPO). RCC and EPO dropped significantly 7 days after a blood transfusion but had normalized after 14 days. Elevated RCC or EPO levels were not predictive of an increase in hemoglobin. Postnatal HbFg/dL was higher in babies who had received transfusions. The authors conclude that blood transfusions depress erythropoiesis in infants with AOP and stimulate HbF synthesis but this effect is not sustained. Reticulocyte counts and erythropoietin levels are unhelpful in predicting recovery from AOP.
机译:作者旨在检验以下假设:输血会抑制健康的早产儿贫血(AOP)婴儿的造血作用。他们还着手寻找可以预测AOP恢复的标志物。每周和输血后对39例早产儿进行血红蛋白浓度,网织红细胞计数(RCC)和促红细胞生成素水平(EPO)的测量。输血后7天,RCC和EPO明显下降,但14天后恢复正常。 RCC或EPO水平升高不能预示血红蛋白增加。接受输血的婴儿的出生后HbFg / dL较高。作者得出的结论是,输血抑制了患有AOP的婴儿的红细胞生成并刺激了HbF的合成,但这种作用并未持续。网织红细胞计数和促红细胞生成素水平无助于预测AOP的恢复。

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