...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pest Management Science >Quantitative structure-activity studies of insect growth regulators: XIX. Effects of substituents on the aromatic moiety of dibenzoylhydrazines on larvicidal activity against the beet armyworm Spodoptera exigua
【24h】

Quantitative structure-activity studies of insect growth regulators: XIX. Effects of substituents on the aromatic moiety of dibenzoylhydrazines on larvicidal activity against the beet armyworm Spodoptera exigua

机译：昆虫生长调节剂的定量结构活性研究：XIX。取代基对二苯甲酰肼的芳香部分的抗甜菜夜蛾甜菜夜蛾幼虫活性的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Larvicidal activity against the beet armyworm, Spodoptera exigua (Hubner), was measured after topical trreatment for a series of N-tert-butyl-dibenzoylhydrazines having various substituents in the benzoyl (A-ring) moiety closer to the tert-butyl-dibenzoylhydrazines having various substituents in the benzoyl (A-ring) moiety closer to the tert-butyl group, the other benzoyl (B-ring) moiety being unsubstituted. The effects of substituents on the larvicidal activity were analyzed using the classical quantitative structure-activity relationship (QSAR) procedure. Introduction of hydrophobic substituents with a small volume into any position was favourable to activity. The existence of electron-withdrawing substituents at ortho positions was also favourable to activity. For multi-substituted cmpounds,physico-chemically unknown unfavourable factors were suggsted to remain after separating common substituent effects derived from QSAR for mono-substituted analogues. With the exdeption of the unsubstituted compound RH-5849 , the effect of substituents in the A-rig moiety on the larvicidal activity was similar to those found with the lepidopteran rice stem borer, Chilo suppressalis (Walker). The larvicidal activity of RH-5849 against S exigua was significantly lower than the value predicted from the correlation between activities against S exigua and C suppressalis. Topical treatment with piperonyl butoxide, a synergist inhibiting oxidative metabolism, slightly enhanced the larvicidal Industry.
机译：在局部处理一系列苯甲酰基（A-环）部分中具有各种取代基的N-叔丁基-二苯甲酰肼后，测定了对甜菜夜蛾（Spodoptera exigua）（Hubner）的杀幼虫活性。靠近叔丁基的苯甲酰基（A-环）部分中的各种取代基，另一个苯甲酰基（B-环）部分未被取代。使用经典的定量构效关系（QSAR）方法分析了取代基对杀幼虫活性的影响。将小体积的疏水取代基引入任何位置都有利于活性。在邻位存在吸电子取代基也有利于活性。对于多取代的cmpounds，在分离出QSAR衍生的单取代类似物的常见取代基效应后，建议保留物理化学未知的不利因素。在未取代的化合物RH-5849的驱除下，A-rig部分中的取代基对杀幼虫活性的影响与鳞翅目水稻stem虫Chilohibialis（Walker）相似。 RH-5849对S. exigua的杀幼虫活性明显低于根据S. exigua和C Chibialis的活性之间的相关性预测的值。抑制氧化代谢的增效剂胡椒基丁醚的局部处理可稍微增强幼虫产业。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号