SYNTHESIS AND NEUROTROPIC ACTIVITY OF SUBSTITUTED 5-DIALKYLAMINOACETYL-3a,4,5,9b-TETRAYDRO-3H- CYCLOPENTA(c)QUINOLINES

G F. Krainova; Yu. B. Vikharev; L. V. Anikina; E. V. Sivtseva; 2; V. A. Glushkov

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SYNTHESIS AND NEUROTROPIC ACTIVITY OF SUBSTITUTED 5-DIALKYLAMINOACETYL-3a,4,5,9b-TETRAYDRO-3H- CYCLOPENTA(c)QUINOLINES

机译：取代的5-二烷基酰胺基乙酰基-3a，4,5,9b-四羟基-3H-环戊基（c）喹啉的合成及神经营养活性

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A series of substituted 5-dialkylaminoacetyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolines were synthesized by amination of the corresponding 5-chloroacetyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolines. The acute toxicity, analgesic activity, and influence of the obtained compounds on the locomotor and exploratory activity in the open-field test were studied.

机译：通过将相应的5-氯乙酰基-3a，4,5,9b-四氢-3H-环戊胺胺化，合成了一系列取代的5-二烷基氨基乙酰基-3a，4,5,9b-四氢-3H-环戊基[c]喹啉[ c]喹啉。研究了野外试验的急性毒性，镇痛活性以及所得化合物对运动和探索活性的影响。

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来源
《Pharmaceutical Chemistry Journal》 |2009年第11期|共4页
作者
G F. Krainova; Yu. B. Vikharev; L. V. Anikina; E. V. Sivtseva; 2; V. A. Glushkov;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
quinolines; amides; Povarov reaction; analgesic activity; open-field test.;

机译：喹啉;酰胺;Povarov反应;镇痛活性;开放视野试验;

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1. SYNTHESIS AND NEUROTROPIC ACTIVITY OF SUBSTITUTED 5-DIALKYLAMINOACETYL-3a,4,5,9b-TETRAYDRO-3H- CYCLOPENTA(c)QUINOLINES [J] . G F. Krainova, Yu. B. Vikharev, L. V. Anikina, Pharmaceutical Chemistry Journal . 2009,第11期

机译：取代的5-二烷基酰胺基乙酰基-3a，4,5,9b-四羟基-3H-环戊基（c）喹啉的合成及神经营养活性
2. Efficient three-component synthesis of diversely substituted tetrahydro-1H-cyclopenta[c]quinolines [J] . Nino Patricia, Caba Marta, Aguilar Nuria, Indian Journal of Chemistry, Section B. Organic Including Medicinal . 2016,第7期

机译：高效取代三氢-1H-环戊基[c]喹啉的三组分合成
3. SYNTHESIS AND NEUROTROPIC ACTIVITY OF NEW PYRIMIDO[4 ',5 ':4,5]THIENO[2,3-b]QUINOLINE DERIVATIVES [J] . Dabaeva V. V., Bagdasaryan M. R., Noravyan A. S., Pharmaceutical Chemistry Journal . 2015,第9期

机译：新型嘧啶并[4'，5'：4,5]噻吩并[2,3-b]喹啉衍生物的合成及神经营养活性
4. Synthesis and Optical Study of Ortho, Meta and Para Methoxy Substituted 2, 4 -Diphenyl Quinoline [C] . L.K. Bedre, B.M. Bahirwar International Conference on "Multidimensional Role of Basic Science in Advanced Technology" . 2019

机译：邻，荟萃和甲氧基取代2,4-二苯基喹啉的合成和光学研究
5. Characterization and Synthesis of 8-Substituted Quinolines and Their Zinc Complexes [D] . Silver, Jessa. 2020

机译：8-取代喹啉及其锌络合物的表征和合成
6. Synthesis and Antileishmanial Activities of Novel 3-Substituted Quinolines [O] . André Gustavo Tempone, Ana Cláudia Melo Pompeu da Silva, Carlos Alberto Brandt, 2005

机译：新型3-取代喹啉的合成及抗leishmanial活性
7. Synthesis and Neurotropic Activity of Novel Quinoline Derivatives [O] . Edmunds Lukevics, Izolda Segal, Alla Zablotskaya, 2013

机译：新型喹啉衍生物的合成及其向神经活性
8. Synthesis and Biological Activity of Nitro-Substituted Cyclopenta-Fused PAH [R] . Goldring, J. M. , Ball, L. M. , Sangaiah, R. , 1986

机译：硝基取代环戊二烯paH的合成及生物活性

SYNTHESIS AND NEUROTROPIC ACTIVITY OF SUBSTITUTED 5-DIALKYLAMINOACETYL-3a,4,5,9b-TETRAYDRO-3H- CYCLOPENTA(c)QUINOLINES

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