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Effects of serotonergic agents on the transport response in rats.

机译:血清素能药物对大鼠运输反应的影响。

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摘要

In two experiments, researchers investigated the effects of manipulating serotonin systems on the transport response and dorsal immobility response in developing rats. In Experiment 1, administration of ketanserin and cinanserin, but not metergoline, suppressed the transport response in 23-day-old rats. These agents were without effect on dorsal immobility durations. In Experiment 2, administration of quipazine to 30-, 40-, and 50-day-old rats resulted in significant increases in transport response intensities and dorsal immobility durations. Results are discussed with respect to the nature of the transport response.
机译:在两个实验中,研究人员研究了操纵5-羟色胺系统对发育中大鼠的运输反应和背侧固定反应的影响。在实验1中,给予酮色林和cinanserin,但不给予美特古林抑制了23日龄大鼠的转运反应。这些药物对背部固定时间没有影响。在实验2中,对30天,40天和50天大的大鼠服用喹哌嗪会导致转运反应强度和背部固定持续时间显着增加。就运输响应的性质讨论了结果。

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