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Involvement of the brain catecholaminergic system in the regulation of dominant behavior.

机译:脑儿茶酚胺能系统参与显性行为的调节。

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The role of the brain catecholaminergic system in establishing dominant-subordinate relationships in mice of different genotypes was studied using inhibitors of tyrosine hydroxylase (alpha-methyl-p-tyrosine) or of dopamine-beta-hydroxylase (FLA-57) or FLA-57 plus the dopamine precursor, DOPA. Demotion in all dominant and subdominant animals was associated with decreased noradrenaline levels, but the aggressive behavior of dominant male mice depended on the noradrenaline/dopamine ratio. Alterations in this relationship seem to have specific effects on social dominance in animals in the micropopulation, as drug-treated mice do not exhibit changes in their general activity. It can be concluded that brain catecholamines are of prime importance in maintenance of dominance.
机译:使用酪氨酸羟化酶(α-甲基-p-酪氨酸)或多巴胺-β-羟化酶(FLA-57)或FLA-57的抑制剂研究了大脑儿茶酚胺能系统在建立不同基因型小鼠的显性从属关系中的作用。加上多巴胺前体DOPA。在所有显性和显性动物中降级与去甲肾上腺素水平降低有关,但是显性雄性小鼠的攻击行为取决于去甲肾上腺素/多巴胺比。这种关系的改变似乎对微型种群中动物的社会支配有特定的影响,因为用药物治疗的小鼠的总体活动没有改变。可以得出结论,脑儿茶酚胺在维持优势中至关重要。

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