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首页> 外文期刊>Pharmaceutical Biology >Correlation Between Antioxidative Power and Anticancer Activity in Herbs from Traditional Chinese Medicine Formulae with Anticancer Therapeutic Effect
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Correlation Between Antioxidative Power and Anticancer Activity in Herbs from Traditional Chinese Medicine Formulae with Anticancer Therapeutic Effect

机译：中药复方具有抗癌作用的抗氧化能力与抗癌活性的相关性

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摘要

Lobeliae chinensis Herba ("ban bian lian"), Rheum offici-nale Baill. ("da huang"), Sanguisorba officinalis Linn, ("di yu"), Agrimonia pilosa Ledeb. ("xian he cao"), and Paris polyphylla Smith ("zhi hua tou") are well-known traditional Chinese medicines. They are commonly used in traditional Chinese medicine formulae against cancer. In this study, the antioxidant and anticancer effects of water extracts of these herbs were investigated. In the antioxidant and anticancer studies, water extracts of di yu, xian he cao, and da huang were show to be the most antioxidative and had the highest growth inhibitory effect on human lung adenocarcinoma A549 cell and human breast cancer MCF-7 cell. By comparing their percentage free radical scavenging capacity (SR%) and percentage growth inhibition on A549 and MCF-7 cells, a positive linear relationship between antioxidant activity and anticancer effect of the five herbal water extracts was found. This suggested that the antioxidants of the herbal water extracts might contribute to their anticancer effects on A549 and MCF-7 cells.
机译：半边莲（Hobelia chinensis Herba），大黄（Rheum offici-nale Baill）。 （“ da huang”），Sanguisorba officinalis Linn（“ di yu”），龙牙草（Agrimonia pilosa Ledeb）。 （“仙鹤草”）和巴黎重叶史密斯（“芝华头”）是著名的传统中药。它们通常用于抗癌的传统中药配方中。在这项研究中，研究了这些草药的水提取物的抗氧化和抗癌作用。在抗氧化剂和抗癌研究中，地榆，仙鹤草和大黄的水提取物显示出对人肺腺癌A549细胞和人乳腺癌MCF-7细胞的最大抗氧化作用，并具有最高的生长抑制作用。通过比较它们清除自由基的能力百分比（SR％）和对A549和MCF-7细胞的生长抑制百分比，发现五种草药水提取物的抗氧化活性与抗癌作用之间呈正线性关系。这表明草药水提取物的抗氧化剂可能有助于其对A549和MCF-7细胞的抗癌作用。

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