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首页> 外文期刊>Pharmaceutical Biology >Analgesic, Anti-inflammatory and Local Anaesthetic Activity of Moringa pterygosperma in Laboratory Animals
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Analgesic, Anti-inflammatory and Local Anaesthetic Activity of Moringa pterygosperma in Laboratory Animals

机译：辣木在植物实验动物中的镇痛，抗炎和局麻作用

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摘要

The methanol extract of Moringa pterygosperma (Morin-gaceae) was used to evaluate its analgesic, anti-inflammatory and local anaesthetic activity in the present study. Analgesic activity was tested in mice using various doses orally. Acetic acid-induced writhing episodes were significantly and dose-dependently reduced. At the same dose, its anti-inflammatory activity was also tested. Carrageenin (a standard inflammatory agent)-induced paw edema in mice was significantly reduced after oral administration. Furthermore, its local anaesthetic activity were tested in frog and guinea pig models, and it was seen that in both animals, the plant (root bark) produces significant local anaesthetic activity.
机译：本研究使用辣木（Morin-gaceae）的甲醇提取物评估其镇痛，抗炎和局部麻醉活性。使用各种口服剂量在小鼠中测试了镇痛活性。乙酸引起的扭体发作显着且剂量依赖性降低。在相同剂量下，还测试了其抗炎活性。口服后，角叉菜胶（一种标准的发炎剂）引起的小鼠爪水肿明显减少。此外，在青蛙和豚鼠模型中测试了其局部麻醉活性，并且发现在两种动物中，植物（根皮）均产生显着的局部麻醉活性。

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