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首页> 外文期刊>Physics in medicine and biology. >Clinical application of the OneDose Patient Dosimetry System for total body irradiation.
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Clinical application of the OneDose Patient Dosimetry System for total body irradiation.

机译：OneDose患者剂量测定系统在全身照射中的临床应用。

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摘要

The OneDose Patient Dosimetry System (Sicel Technologies) is a new dosimeter based on metal oxide semiconductor field-effect transistor technology and designed for the in vivo measurement of patient dose during radiotherapy. In vivo dosimetry for total body irradiation (TBI) is challenging due to the extended treatment distance, low dose rates and beam spoilers. Phantom results confirm the suitability of the dosimeter for TBI in terms of inherent build-up, post-irradiation fading, accuracy, reproducibility, linearity and temperature dependence. Directional dependence is significant and should be taken into account. The OneDose dosimeters were also trialed in vivo for two TBI patients and the dose measured compared to conventional dosimeter measurements using an ionization chamber and thermoluminescent dosimeters (TLD), with agreement to within 2.2% and 3.9%, respectively. Phantom and patient results confirm that the OneDose patient dosimetry system is a practical and convenient alternative to TLDs for TBI in vivo dosimetry. For increased confidence in results with this dosimeter, we recommend that two dosimeters be used for each site of interest.
机译：OneDose患者剂量测定系统（Sicel Technologies）是一种基于金属氧化物半导体场效应晶体管技术的新型剂量计，设计用于在放射治疗期间体内测量患者的剂量。由于延长的治疗距离，低剂量率和光束扰流器，用于全身辐射（TBI）的体内剂量测定法具有挑战性。虚拟结果证实了剂量计适用于TBI的固有累积，照射后褪色，准确性，可再现性，线性和温度依赖性。方向依赖性很重要，应予以考虑。还对两名TBI患者进行了OneDose剂量计的体内试验，与使用电离室和热发光剂量计（TLD）进行的常规剂量计测量相比，所测量的剂量分别在2.2％和3.9％之内。幻像和患者结果证实，OneDose患者剂量测定系统是TLD体内剂量测定的TLD的一种实用方便的替代方法。为了增加对该剂量计结果的信心，我们建议对每个感兴趣的位置使用两个剂量计。

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