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首页> 外文期刊>Phlebology >A comparison of low-molecular-weight heparin and combined therapy of low-molecular-weight heparin with an anti-inflammatory agent in the treatment of superficial vein thrombosis.
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A comparison of low-molecular-weight heparin and combined therapy of low-molecular-weight heparin with an anti-inflammatory agent in the treatment of superficial vein thrombosis.

机译：低分子肝素与低分子肝素与抗炎药联合治疗浅表静脉血栓形成的比较。

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摘要

OBJECTIVES: The optimal treatment of superficial vein thrombosis (SVT) of the leg has not been determined yet. The aim of this study is to evaluate the efficacy of low-molecular-weight heparin (LMWH) as compared with combined therapy of LMWH with an anti-inflammatory agent in treatment of SVT. METHODS: Fifty patients with SVT of the greater saphenous vein were randomly assigned to be treated with Ca-nadroparin 190 IUAxa/kg in a single dose or with same dose of Ca-nadroparin and 60 mg oral acemetacine twice daily for 10 days. The efficacy of the two treatments to relieve symptoms and signs was evaluated by using visual analogue scale. RESULTS: Significant improvements were achieved for both groups after the treatment in terms of all four symptoms (P < 0.001). Treatment scores were in favour of LMWH with anti-inflammatory agent treatment group to relieve all four symptoms. The most significant and remarkable results obtained were for the reduction of pain and local tenderness (P < 0.05). No patient experienced major complications or mortality in either group. CONCLUSION: The results of this study suggest that the combined therapy of LMWH with an anti-inflammatory agent is more effective than LMWH. It may be an important option in the standard treatment of SVT.
机译：目的：尚未确定腿浅表血栓形成（SVT）的最佳治疗方法。这项研究的目的是评估低分子量肝素（LMWH）与LMWH与抗炎药联合治疗SVT的疗效。方法：将50例大隐静脉SVT患者随机分为单剂量或相同剂量的钙-萘达普林190 IUAxa / kg或60 mg口服醋美他汀口服，每天两次，连续10天。使用视觉模拟量表评估了两种治疗缓解症状和体征的功效。结果：治疗后两组的所有四个症状均取得了显着改善（P <0.001）。抗炎药治疗组的治疗得分均优于LMWH，以减轻所有四个症状。获得的最显着和最显着的结果是减少了疼痛和局部压痛（P <0.05）。两组均无患者发生重大并发症或死亡。结论：本研究结果表明，LMWH与抗炎药联合治疗比LMWH更有效。在SVT的标准治疗中，这可能是一个重要的选择。

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    《Phlebology》 |2009年第2期|共5页
  • 作者

    Uncu H;

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  • 中图分类 内科学;
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