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Modellierung und effektive numerische Simulation von chromatographischen Trennprozessen im SMB-Betrieb

机译:SMB操作中色谱分离过程的建模和有效数值模拟

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摘要

Chromatographic separation processes provide a powerful tool for the separation of mixtures in which the components have different adsorption affinities, especially when high purities are required. In this area, simulated moving bed (SMB) technology is becoming an important technique for large- scale continuous chromatographic separation processes since it provides the advantages of a continuous countercurrent operation while avoiding the technical problem of a true moving bed. Because of the complex dynamics of the process, the choice of the optimal operation parameters and the control of the process in order to keep the product specifications at any time is not straightforward. For this challenging task, a reliable dynamic model of the process is necessary which is accurate enough as well as efficient enough in order to permit its online use for model based control. The purpose of this contribution is to review the state of the art in dynamic modeling of SMB chromatographic separation processes, highlighting new trends and results in the design of computationally effective simulation models suitable for online applications.
机译:色谱分离过程为分离混合物提供了强大的工具,在这些混合物中,组分具有不同的吸附亲和力,尤其是在需要高纯度的情况下。在该领域,模拟移动床(SMB)技术正成为大规模连续色谱分离过程的重要技术,因为它提供了连续逆流操作的优势,同时又避免了真正的移动床的技术问题。由于过程的复杂性,为随时保持产品规格而选择最佳操作参数和过程控制并非易事。对于这一具有挑战性的任务,必须要有一个可靠的过程动态模型,该模型必须足够准确和有效,以使其可以在线用于基于模型的控制。该贡献的目的是回顾SMB色谱分离过程动态建模的最新技术,重点介绍适用于在线应用的计算有效仿真模型设计的新趋势和结果。

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