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Synthetic and Systems Biotechnology

【机译】：合成和生物技术系统

ISSN：-
出版周期：Quarterly
语言：English

起始发布年份：2016
出版者：[Beijing, China] : KeAi Communications Co., [2016]-
出版地：China

数据库引入：PubMed: v1n1, Mar. 2016-, PMC

MeSH词表主题词：Biotechnology*; Systems Biology

备注：Description based on Volume 1, Issue 1 (March 2016); title from journal home page展开▼

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1.Simple glycolipids of microbes: Chemistry biological activity and metabolic engineering

机译：微生物的简单糖脂：化学生物活性和代谢工程
- 作者：Ahmad Mohammad Abdel-Mawgoud;Gregory Stephanopoulos
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2018年第1期
- Biosurfactant Glycolipids biosynthesis Glycosyl/acyl transferases Glycosides Physiological roles Lipid biotechnology;
2.Expanding beyond canonical metabolism: Interfacing alternative elements synthetic biology and metabolic engineering

机译：超越常规代谢扩展：接口替代元素合成生物学和代谢工程
- 作者：Kevin B. Reed;Hal S. Alper
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2018年第1期
- Metabolic engineering Synthetic biology Unnatural metabolism Halogenation Cellular factories Non-canonical elements;
3.Methods and approaches to disease mechanisms using systems kinomics

机译：使用系统动力学的疾病机理的方法和途径
- 作者：Alicia Berard;Andrea Kroeker;Peter McQueen;Kevin M. Coombs
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2018年第1期
4.Comprehensive relative quantitative metabolomics analysis of lycopodium alkaloids in different tissues of Huperzia serrata

机译：蛇足石杉不同组织中的麦冬总生物碱的相对定量代谢组学综合分析
- 作者：Shiwen Wu;Zhen Fan;Youli Xiao
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2018年第1期
- Huperzia serrata Different tissues Metabolomics Metabolite identification In-silico fragmentations prediction;
5.Engineering metabolic pathways in Amycolatopsis japonicum for the optimization of the precursor supply for heterologous brasilicardin congeners production

机译：工程化日本扁桃中的代谢途径以优化异源油菜素卡因同源物生产的前体供应
- 作者：Paul N. Schwarz;Luisa Roller;Andreas Kulik;Wolfgang Wohlleben;Evi Stegmann
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2018年第1期
- Norcardia terpenica IFM0406 Mevalonate pathway Isoprenoids Prenyltransferases;
6.Investigating the consequences of asymmetric endoplasmic reticulum inheritance in Saccharomyces cerevisiae under stress using a combination of single cell measurements and mathematical modelling

机译：使用单细胞测量和数学建模相结合的方法研究应激下酿酒酵母中不对称内质网遗传的后果
- 作者：Felix R.H. Jonas;Kate E. Royle;Rochelle Aw;Guy-Bart V. Stan;Karen M. Polizzi
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2018年第1期
- Adaptation Asymmetric cell division Endoplasmic reticulum stress Unfolded protein response Saccharomyces cerevisiae;
7.Puromycin A B and C cryptic nucleosides identified from Streptomyces alboniger NRRL B-1832 by PPtase-based activation

机译：嘌呤霉素AB和C通过基于PPtase的活化从白链霉菌NRRL B-1832中鉴定出的隐性核苷
- 作者：Xiaoli Yan;Benyin Zhang;Wenya Tian;Qi Dai;Xiaoqin Zheng;Ke Hu;Xinxin Liu;Zixin Deng;Xudong Qu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2018年第1期
- Puromycin Phosphopantetheinyl transferase Gene activation Streptomyces alboniger Genome mining;
8.Genomic and transcriptional changes in response to pinene tolerance and overproduction in evolved Escherichia coli

机译：基因组和转录变化响应进化中的大肠杆菌对over烯的耐受性和过量生产
- 作者：Fu-Xing Niu;Yuan-Bin Huang;Liang-Nian Ji;Jian-Zhong Liu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第3期
- Comparative omics analysis CRISPRa CRISPRi Pinene Escherichia coli Biosynthesis;
9.Metabolic engineering of Corynebacterium glutamicum S9114 based on whole-genome sequencing for efficient N-acetylglucosamine synthesis

机译：基于全基因组测序的谷氨酸棒杆菌S9114的代谢工程可有效合成N-乙酰氨基葡萄糖
- 作者：Chen Deng;Xueqin Lv;Yanfeng Liu;Jianghua Li;Wei Lu;Guocheng Du;Long Liu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第3期
- C. glutamicum Complete genome N-acetylglucosamine Metabolic engineering;
10.A novel synchronization approach using synthetic magnetic Escherichia coli

机译：一种使用合成磁性大肠杆菌的新型同步方法
- 作者：Hua Ling;Matthew Wook Chang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第3期
- Cell cycle Microfluidic synchronization Magnetic fluorescent nanoparticles Escherichia coli;
11.The road less traveled: A new phosphorothioate antiviral defense mechanism discovered in Archaea

机译：人迹罕至的道路：古细菌中发现的一种新的硫代磷酸酯抗病毒防御机制
- 作者：Michael S. DeMott;Peter C. Dedon
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第3期
12.Efficient biosynthesis of 2-keto-D-gluconic acid by fed-batch culture of metabolically engineered Gluconobacter japonicus

机译：代谢工程改造的日本葡糖杆菌的分批补料培养有效合成2-酮-D-葡萄糖酸
- 作者：Weizhu Zeng;Wen Cai;Li Liu;Guocheng Du;Jian Chen;Jingwen Zhou
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第3期
- 2-Keto-d-gluconic acid Gluconobacter Dehydrogenase Homologous recombination Fed-batch fermentation;
13.Depiction of secondary metabolites and antifungal activity of Bacillus velezensis DTU001

机译：Velez velezensis DTU001的次生代谢产物的描述和抗真菌活性
- 作者：Sagarika Devi;Heiko T. Kiesewalter;Renátó Kovács;Jens Christian Frisvad;Tilmann Weber;Thomas Ostenfeld Larsen;Ákos T. Kovács;Ling Ding
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第3期
- Bacillus velezensis Candida albicans Secondary metabolites Biocontrol Biofilm;
14.The statistical power of k-mer based aggregative statistics for alignment-free detection of horizontal gene transfer

机译：基于k-mer的聚合统计量对水平基因转移的无比对检测的统计能力
- 作者：Guan-Da Huang;Xue-Mei Liu;Tian-Lai Huang;Li- C. Xia
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第3期
- Alignment-free sequence comparison k-mer Horizontal gene transfer Statistical power;
15.A novel D(−)-lactic acid-inducible promoter regulated by the GntR-family protein D-LldR of Pseudomonas fluorescens

机译：由荧光假单胞菌的GntR家族蛋白D-LldR调控的新型D（-）-乳酸诱导型启动子
- 作者：Kalpana Singh;Satish Kumar Ainala;Yeonhee Kim;Sunghoon Park
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第3期
- Lactic acid Enantiomer Biosensor Repression;
16.Detailed profiling of carbon fixation of in silico synthetic autotrophy with reductive tricarboxylic acid cycle and Calvin-Benson-Bassham cycle in Esherichia coli using hydrogen as an energy source

机译：使用氢作为能源利用大肠杆菌中的还原三羧酸循环和Calvin-Benson-Bassham循环对合成的有机硅自生碳的碳固定进行详细分析
- 作者：Hsieh-Ting-Yang Cheng;Shou-Chen Lo;Chieh-Chen Huang;Tsung-Yi Ho;Ya-Tang Yang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第3期
- Reductive tricarboxylic acid cycle Calvin-Benson-Bassham cycle Carbon fixation Metabolism;
17.CRISPR-PIN: Modifying gene position in the nucleus via dCas9-mediated tethering

机译：CRISPR-PIN：通过dCas9介导的束缚来修饰基因在细胞核中的位置
- 作者：Jyun-Liang Lin;Holly Ekas;Matthew Deaner;Hal S. Alper
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第2期
- CRISPR Chromosome organization Chromosome biology Gene positioning Synthetic biology;
18.Simultaneously down-regulation of multiplex branch pathways using CRISPRi and fermentation optimization for enhancing β-amyrin production in Saccharomyces cerevisiae

机译：同时使用CRISPRi下调多重分支途径并优化发酵以增强酿酒酵母中β-胰岛淀粉样多肽的生产
- 作者：Jiangping Ni;Genlin Zhang;Lei Qin;Jun Li;Chun Li
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第2期
- β-amyrin CRISPRi Transcriptional regulation Saccharomyces cerevisiae;
19.Efficient editing DNA regions with high sequence identity in actinomycetal genomes by a CRISPR-Cas9 system

机译：通过CRISPR-Cas9系统在放线菌基因组中高效编辑具有高序列同一性的DNA区域
- 作者：Jingjun Mo;Shuwen Wang;Wan Zhang;Chunyu Li;Zixin Deng;Lixin Zhang;Xudong Qu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第2期
- Biosynthesis Polyketide synthase CRISPR/Cas9 Antimycin Actinobacteria;
20.Resistance mechanisms and reprogramming of microorganisms for efficient biorefinery under multiple environmental stresses

机译：在多种环境压力下高效生物精炼厂的微生物抗性机制和重编程
- 作者：Ke Xu;Yun Seo Lee;Jun Li;Chun Li
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第2期
- Biorefinery Environmental stresses Microbial resistance mechanism Synthetic biology Bioprocess integration;
21.Design and synthesis of synthetic UP elements for modulation of gene expression in Escherichia coli

机译：设计和合成用于调控大肠杆菌中基因表达的合成UP元件
- 作者：Kristin V. Presnell;Madeleine Flexer-Harrison;Hal S. Alper
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第2期
- UP element Promoter engineering Expression modulation;
22.The phage T4 DNA ligase mediates bacterial chromosome DSBs repair as single component non-homologous end joining

机译：噬菌体T4 DNA连接酶介导细菌染色体DSB的修复因为单组分非同源末端连接
- 作者：Tianyuan Su;Fapeng Liu;Yizhao Chang;Qi Guo;Junshu Wang;Qian Wang;Qingsheng Qi
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第2期
- T4 DNA ligase DNA double-strand breaks Non-homologous end joining CRISPR-Cas9;
23.Systematically investigating the key features of the DNase deactivated Cpf1 for tunable transcription regulation in prokaryotic cells

机译：系统研究DNase失活的Cpf1在原核细胞中可调节转录调控的关键特征
- 作者：Chensi Miao;Huiwei Zhao;Long Qian;Chunbo Lou
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第1期
24.Crystal structure of the condensation domain from lovastatin polyketide synthase

机译：洛伐他汀聚酮化合物合酶的缩合域的晶体结构
- 作者：Lei Wang;Meijuan Yuan;Jianting Zheng
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第1期
25.Characterization of the positive SARP family regulator PieR for improving piericidin A1 production in Streptomyces piomogeues var. Hangzhouwanensis

机译：表征SARP家族正调节剂PieR的方法以改善链霉菌链霉菌中Piericidin A1的产生。杭州湾
- 作者：Yan Li;Lingxin Kong;Jufang Shen;Qing Wang;Qian Liu;Weinan Yang;Zixin Deng;Delin You
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第1期
- ɑ-pyridone antibiotic Transcriptional regulation SARP family regulator Secondary metabolic Streptomyces;
26.Engineering and modification of microbial chassis for systems and synthetic biology

机译：用于系统和合成生物学的微生物底盘的工程和改造
- 作者：Haotian Chi;Xiaoli Wang;Yue Shao;Ying Qin;Zixin Deng;Lianrong Wang;Shi Chen
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第1期
- Microbial chassis Systems biology Synthetic biology;
27.Streptomyces avermitilis industrial strain as cell factory for Ivermectin B1a production

机译：阿维链霉菌工业菌株作为伊维菌素B1a生产的细胞工厂
- 作者：Qian Deng;Liqiongzi Xiao;Yang Liu;Lixin Zhang;Zixin Deng;Changming Zhao
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第1期
- Avermectin Ivermectin Meilingmycin Domain swapping Heterologo-us biosynthesis;
28.A LuxR family transcriptional regulator AniF promotes the production of anisomycin and its derivatives in Streptomyces hygrospinosus var. beijingensis

机译：LuxR家族的转录调节因子AniF促进潮霉素链霉菌变种中茴香霉素及其衍生物的产生。北京
- 作者：Jufang Shen;Lingxin Kong;Yan Li;Xiaoqing Zheng;Qing Wang;Weinan Yang;Zixin Deng;Delin You
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第1期
- Anisomycin Agricultural Antibiotic120 Biosynthesis AniF LuxR regulator Streptomyces;
29.Comparative functional genomics of the acarbose producers reveals potential targets for metabolic engineering

机译：阿卡波糖生产者的比较功能基因组学揭示了代谢工程的潜在目标
- 作者：Huixin Xie;Qinqin Zhao;Xin Zhang;Qianjin Kang;Linquan Bai
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第1期
- Acarbose Comparative genomics Overproduction Regulation;
30.Miniaturisation of high-throughput plasmid DNA library preparation for next-generation sequencing using multifactorial optimisation

机译：使用多因素优化的下一代测序的高通量质粒DNA文库制备的小型化
- 作者：Lorna Suckling;Ciaran McFarlane;Chelsea Sawyer;Stephen P. Chambers;Richard I. Kitney;David W. McClymont;Paul S. Freemont
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第1期
31.Synergistic drug combinations prediction by integrating pharmacological data

机译：通过整合药理数据预测协同药物组合
- 作者：Chengzhi Zhang;Guiying Yan
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第1期
- Synergistic drug combinations Factorization machines Computational methods;
32.Benchmarking two Saccharomyces cerevisiae laboratory strains for growth and transcriptional response to methanol

机译：基准测试两个酿酒酵母实验室菌株对甲醇的生长和转录反应
- 作者：Monica I. Espinosa;Thomas C. Williams;Isak S. Pretorius;Ian T. Paulsen
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第4期
- Yeast Methylotrophy Synthetic biology Metabolic engineering MIG3 Methanol;
33.Brocaeloid D a novel compound isolated from a wheat pathogenic fungus Microdochium majus 99049

机译：Brocaeloid D一种从小麦致病性真菌Madhus majus 99049分离的新型化合物
- 作者：Jingyu Zhang;Zhenzhen Wang;Zhijun Song;Loganathan Karthik;Chengjian Hou;Guoliang Zhu;Lan Jiang;Jianying Han;Rong Ma;Li Li;Lixin Zhang;Xueting Liu;Tom Hsiang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第4期
- Wheat pathogenic fungus Anticancer Antibacterial Natural product;
34.Simplified methodology for a modular and genetically expanded protein synthesis in cell-free systems

机译：在无细胞系统中模块化和遗传扩展的蛋白质合成的简化方法
- 作者：Yonatan Chemla;Eden Ozer;Michael Shaferman;Ben Zaad;Rambabu Dandela;Lital Alfonta
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第4期
- Cell free system;
- Genetic code expansion;
- Thio-lysine;
- Simplified extract preparation;
35.Engineering strong and stress-responsive promoters in Bacillus subtilis by interlocking sigma factor binding motifs

机译：通过互锁的sigma因子结合基序工程化枯草芽孢杆菌中强大的应激反应启动子
- 作者：Yang Wang;Yanan Shi;Litao Hu;Guocheng Du;Jian Chen;Zhen Kang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第4期
- Synthetic biology;
- Transcription;
- Promoter engineering;
- Stress-responsive;
36.Methods to reduce variability in E. Coli-based cell-free protein expression experiments

机译：减少基于大肠杆菌的无细胞蛋白质表达实验中变异性的方法
- 作者：Jared L. Dopp;Yeong Ran Jo;Nigel F. Reuel
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第4期
- Cell-free protein synthesis;
- CFPS;
- Cell extract;
37.Phosphate limitation increases coenzyme Q10 production in industrial Rhodobacter sphaeroides HY01

机译：磷酸盐限制增加了球形红球菌HY01中辅酶Q10的产生
- 作者：Lu Zhang;Leshi Liu;Ke-Feng Wang;Lan Xu;Liming Zhou;Weishan Wang;Chuan Li;Zheng Xu;Tong Shi;Haihong Chen;Yuanhang Li;Hui Xu;XiuLiang Yang;Zhichun Zhu;Biqin Chen;Dan Li;Guanghuang Zhan;Si-Liang Zhang;Li-Xin Zhang;Gao-Yi Tan
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第4期
- CoQ;
38.Streamlining the preparation of endotoxin-free ClearColi cell extract with autoinduction media for cell-free protein synthesis of the therapeutic protein crisantaspase

机译：使用自动诱导培养基简化无内毒素 ClearColi细胞提取物的制备过程以无细胞蛋白质合成治疗性蛋白质crisantaspase
- 作者：J. Porter Hunt;Emily Long Zhao;Mehran Soltani;Madison Frei;J. Andrew D. Nelson;Bradley C. Bundy
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第4期
- Auto-induction;
- Autoinduction;
- Cell-free protein synthesis;
- CFPS;
- Endotoxin-free;
- Crisantaspase;
- Clearcoli;
39.Resolution of deep divergence of club fungi (phylum Basidiomycota)

机译：解决俱乐部真菌（Basidiomycota）的深层分歧
- 作者：Hongliang Mao;Hao Wang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第4期
- Fungi;
- Basidiomycota;
- Phylogenetics;
- Phylogenomics;
- CVTree;
40.Corrigendum to Rapid evolution of regulatory element libraries for tunable transcriptional and translational control of gene expression Synth Syst Biotechnol 2 (4) (2017) 295–301

机译：更正用于基因表达的可调转录和翻译控制的调控元件库的快速进化 Synth Syst Biotechnol 2（4）（2017）295-301
- 作者：Erqing Jin;Lynn Wong;Yun Jiao;Jake Engel;Benjamin Holdridge;Peng Xu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2019年第4期
41.Biofilm architecture: An emerging synthetic biology target

机译：生物膜建筑：新兴的合成生物学目标
- 作者：Stephen J. Kassinger;Monique L. van Hoek
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第1期
- Synthetic biology;
- Tunable;
- Biofilm engineering;
42.Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast

机译：可编程聚酮化合物生物合成平台用于在酵母中生产芳香族化合物
- 作者：Tadas Jakočiūnas;Andreas K. Klitgaard;Eftychia Eva Kontou;Julie Bang Nielsen;Emil Thomsen;David Romero-Suarez;Kai Blin;Christopher J. Petzold;Jennifer W. Gin;Yaojun Tong;Charlotte Held Gotfredsen;Pep Charusanti;Rasmus J.N. Frandsen;Tilmann Weber;Sang Yup Lee;Michael K. Jensen;Jay D. Keasling
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第1期
- Natural products;
- Synthetic biology;
- Aromatic polyketides;
- CRISPR/Cas9;
- Polyketide;
- Production platform in eukaryotes;
- Metabolic engineering;
- Biotechnology;
43.The X-factor: Enhanced β-oxidation on intracellular triacylglycerols enabling overproduction of polyketide drug-like molecules in microorganisms

机译：X因子：增强细胞内三酰基甘油的β氧化作用使微生物中的聚酮化合物类药物分子过量生产
- 作者：Shan Wang;Hai Deng
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第1期
44.Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production

机译：释放能量存储的能量：工程化β-氧化途径以生产聚酮化合物
- 作者：Bin Wang;Huimin Zhao
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第1期
- Polyketide;
- Beta-oxidation pathway;
- Metabolic engineering;
- Triacylglycerols;
45.Designing chimeric enzymes inspired by fungal cellulosomes

机译：设计受真菌纤维素启发的嵌合酶
- 作者：Sean P. Gilmore;Stephen P. Lillington;Charles H. Haitjema;Randall de Groot;Michelle A. OMalley
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第1期
- Cellulosome;
- Dockerin;
- Scaffoldin;
- Anaerobic fungi;
- Thermophile;
- Enzyme;
46.Unlocking a new target for streptomycetes strain improvement

机译：揭开链霉菌菌株改良的新目标
- 作者：Yuan Chen;Jackie Metz;René K. Miller-Xavier;Guojun Wang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第1期
- Polyketide;
- Streptomyces;
- Strain Improvement;
- Triacylglycerol;
- β-oxidation;
- Acetyl-CoA;
47.Boosting polyketides production in cell factories

机译：促进细胞工厂中聚酮化合物的生产
- 作者：Wen-bing Jin;Chun-Jun Guo
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第1期
48.Complete genome sequence of high-yield strain S. lincolnensis B48 and identification of crucial mutations contributing to lincomycin overproduction

机译：高产菌株林肯链球菌B48的完整基因组序列和鉴定导致林可霉素过量生产的关键突变
- 作者：Ruida Wang;Fanjing Kong;Haizhen Wu;Bingbing Hou;Yajing Kang;Yuan Cao;Shiwei Duan;Jiang Ye;Huizhan Zhang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第2期
- Lincomycin;
- Comparative genomics;
- Regulation;
- Overproduction;
49.Coordinated regulation for nature products discovery and overproduction in Streptomyces

机译：链霉菌中天然产物发现和过量生产的协调监管
- 作者：Qun Zhou;Shuqing Ning;Yunzi Luo
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第2期
- Gene expression regulation;
- Natural products;
50.Prudently conduct the engineering and synthesis of the SARS-CoV-2 virus

机译：谨慎进行SARS-CoV-2病毒的工程和合成
- 作者：Peng Gao;Shiwen Ma;Daru Lu;Carl Mitcham;Yijia Jing;Guoyu Wang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第2期
- Engineering SARS-CoV-2 virus;
- Dual-use;
- Risk;
- Biosafety/Biosecurity;
- Regulation;
51.Toward fine-tuned metabolic networks in industrial microorganisms

机译：建立工业微生物中微调的代谢网络
- 作者：Ning Li;Weizhu Zeng;Sha Xu;Jingwen Zhou
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第2期
- Fine-tuned regulation;
- Protein engineering;
- Upregulation;
- Downregulation;
- Dynamic regulation;
52.An aurora of natural products-based drug discovery is coming

机译：基于天然产物的药物发现的极光即将到来
- 作者：Yaojun Tong;Zixin Deng
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第2期
53.Metabolic engineering of a methyltransferase for production of drug precursors demecycline and demeclocycline in Streptomyces aureofaciens

机译：甲基转移酶的代谢工程用于生产金黄色链霉菌中的药物前体德美环素和德美环素
- 作者：Weinan Yang;Lingxin Kong;Qing Wang;Zixin Deng;Delin You
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
- Demecycline;
- Demeclocycline;
54.Cell-free synthesis system-assisted pathway bottleneck diagnosis and engineering in Bacillus subtilis

机译：无细胞合成系统辅助枯草芽孢杆菌的途径瓶颈诊断与工程
- 作者：Rongzhen Tian;Minghu Wang;Jintian Shi;Xiaolong Qin;Haoyu Guo;Xuanjie Jia;Jianghua Li;Long Liu;Guocheng Du;Jian Chen;Yanfeng Liu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
- Pathway bottleneck diagnosis;
- Cell-free synthesis system;
55.Improving the reaction mix of a Pichia pastoris cell-free system using a design of experiments approach to minimise experimental effort

机译：使用实验方法设计来改善巴斯德毕赤酵母无细胞系统的反应混合物
- 作者：Alex J. Spice;Rochelle Aw;Daniel G. Bracewell;Karen M. Polizzi
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
- Cell-free protein synthesis;
56.Silk fibroin as an additive for cell-free protein synthesis

机译：丝素蛋白作为无细胞蛋白质合成的添加剂
- 作者：Marilyn S. Lee;Chia-Suei Hung;Daniel A. Phillips;Chelsea C. Buck;Maneesh K. Gupta;Matthew W. Lux
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
- Cell-free systems;
- Cell-free protein synthesis;
- CFPS;
- Silk fibroin;
- Preservation;
57.Challenges and advances in genome mining of ribosomally synthesized and post-translationally modified peptides (RiPPs)

机译：核糖体合成和翻译后修饰的肽（RiPPs）基因组挖掘的挑战和进展
- 作者：Zheng Zhong;Beibei He;Jie Li;Yong-Xin Li
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
58.From nature to nurture: Essence and methods to isolate robust methanotrophic bacteria

机译：从自然到养育：隔离强大的甲烷营养细菌的本质和方法
- 作者：Haritha Meruvu;Hui Wu;Ziyue Jiao;Liyan Wang;Qiang Fei
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
- Methanotrophs;
- Isolation;
- Culture medium;
- High throughput;
- Adaptive laboratory evolution;
59.Harnessing sub-organelle metabolism for biosynthesis of isoprenoids in yeast

机译：利用亚细胞器代谢促进酵母中类异戊二烯的生物合成
- 作者：Xuan Cao;Shan Yang;Chunyang Cao;Yongjin J. Zhou
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
- Isoprenoids;
- Yeast;
- Compartmentalization;
- Sub-organelle metabolism;
60.Discovery and modification of cytochrome P450 for plant natural products biosynthesis

机译：用于植物天然产物生物合成的细胞色素P450的发现和修饰
- 作者：Xiaonan Liu;Xiaoxi Zhu;Hui Wang;Tian Liu;Jian Cheng;Huifeng Jiang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
- P450 enzymes;
- Plant natural products;
- Synthetic biology;
61.Advances on systems metabolic engineering of Bacillus subtilis as a chassis cell

机译：枯草芽孢杆菌作为底盘细胞的系统代谢工程研究进展
- 作者：Mengjie Xiang;Qian Kang;Dawei Zhang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
- Systems metabolic engineering;
- Systematic biology;
- Synthetic biology;
- Evolutionary engineering;
62.Methodologies for preparation of prokaryotic extracts for cell-free expression systems

机译：用于制备用于无细胞表达系统原核提取物的方法
- 作者：Stephanie D. Cole;Aleksandr E. Miklos;Abel C. Chiao;Zachary Z. Sun;Matthew W. Lux
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
- Cell-free systems;
- Cell-free expression;
- Cell-free extract;
- Synthetic biology;
- Methods;
63.Expanding application of CRISPR-Cas9 system in microorganisms

机译：CRISPR-CAS9系统在微生物中的应用
- 作者：Jing Zhao;Huan Fang;Dawei Zhang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
- CRISPR-Cas9 system;
- Microorganisms;
- Off-target;
- Cas9 toxicity;
- sgRNA;
64.Corrigendum to Site directed mutagenesis as a precision tool to enable synthetic biology with engineered modular polyketide synthases Synth Syst Biotechnol 5 (2) (2020) 62–80

机译：站点定向诱变作为精密工具以使合成生物学与工程模块化聚酮合成酶实现合成生物学合成酶Synth Syst Biotechnol 5（2）（2020）62-80
- 作者：Erin E. Drufva;Elijah G. Hix;Constance B. Bailey
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
65.Microbial soluble aromatic prenyltransferases for engineered biosynthesis

机译：用于工程化生物合成的微生物可溶性芳族戊基转移酶
- 作者：He-Ping Chen;Ikuro Abe
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第2期
- Microbial prenyltransferase;
- Biosynthesis;
- Enzyme engineering;
- Prenylation;
- Synthetic biology;
66.Screening neutral sites for metabolic engineering of methylotrophic yeast

机译：筛选甲基营养酵母代谢工程的中性位点
- 作者：Wei Yu;Jiaoqi Gao;Xiaoxin Zhai;Yongjin J. Zhou
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第2期
- Neutral sites;
67.Systematic optimization of the yeast cell factory for sustainable and high efficiency production of bioactive ginsenoside compound K

机译：酵母细胞厂的系统优化可持续和高效生产生物活性人参皂苷类化合物K.
- 作者：Pingping Wang;Jiali Wang;Guoping Zhao;Xing Yan;Zhihua Zhou
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第2期
- Compound K;
- UDP-Glucose;
- Glycosylation efficiency;
- Cell factory;
- Synthetic biology;
68.Rationally optimized generation of integrated

机译：合理优化的集成生成
- 作者：Muhammad Hammad Hussain;Qi Hong;Waqas Qamar Zaman;Ali Mohsin;Yanlong Wei;Ning Zhang;Hongqing Fang;Zejian Wang;Haifeng Hang;Yingping Zhuang;Meijin Guo
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第2期
- Escherichia coli;
69.The Fold-Illuminator: A low-cost portable and disposable incubator-illuminator device

机译：折灯照明器：低成本便携式和一次性培养箱 - 发光器装置
- 作者：Logan R. Burrington;Emran Baryal;Katherine Hui;Emmett Lambert;Sarah T. Harding;Javin P. Oza
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第2期
- Illuminator;
- Incubator;
- Fluorescent reporter;
- Education;
- Diagnostics;
- Frugal science;
70.Development of synthetic biology tools to engineer

机译：为工程师开发合成生物学工具
- 作者：Jucan Gao;Lihong Jiang;Jiazhang Lian
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第2期
- Pichia pastoris;
71.Comparison of gut microbiota in autism spectrum disorders and neurotypical boys in China: A case-control study

机译：肠道微生物在中国自闭症谱系障碍和神经典型男孩的比较：案例对照研究
- 作者：Fang Ye;Xinying Gao;Zhiyi Wang;Shuman Cao;Guangcai Liang;Danni He;Zhitang Lv;Liming Wang;Pengfei Xu;Qi Zhang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第2期
- Autism spectrum disorders;
- Gut microbiome;
- China;
72.Complex natural product production methods and options

机译：复杂的天然产品生产方法和选择
- 作者：Dongwon Park;Girish Swayambhu;Thomas Lyga;Blaine A. Pfeifer
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第1期
- Natural product;
- Bio-manufacturing;
- Native host;
- Heterologous host;
- Biosynthesis;
73.Genomic scanning enabling discovery of a new antibacterial bicyclic carbamate-containing alkaloid

机译：基因组扫描能够发现发现含有含有新的抗菌双环氨基甲酸的生物碱
- 作者：Qing Fang;Linrui Wu;Caroline Urwald;Morgane Mugat;Shan Wang;Kwaku Kyeremeh;Carol Philips;Samantha Law;Yongjun Zhou;Hai Deng
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第1期
74.Expression of fungal biosynthetic gene clusters in

机译：真菌生物合成基因簇的表达
- 作者：Zihe Liu;Zhenquan Lin;Jens Nielsen
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第1期
- Natural product discovery;
- Cross-species engineering;
- Spliceosome;
- High-throughput BGC cloning;
- Synthetic biology;
- Yeast;
75.Chemical modifications of proteins and their applications in metalloenzyme studies

机译：蛋白质的化学修饰及其在核酶研究中的应用
- 作者：Nathchar Naowarojna;Ronghai Cheng;Juan Lopez;Christina Wong;Lu Qiao;Pinghua Liu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第1期
- Metalloenzymes;
- Biorthogonal reactions;
- Protein engineering;
- Non-canonical amino acids;
- Biocatalysis;
76.Disaccharide phosphorylases: Structure catalytic mechanisms and directed evolution

机译：二糖磷酸化酶：结构催化机制和定向演化
- 作者：Shangshang Sun;Chun You
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第1期
- Disaccharide phosphorylase;
- Classification;
- Structure and domains;
- Substrate specificity;
- Enzyme engineering;
77.Site directed mutagenesis as a precision tool to enable synthetic biology with engineered modular polyketide synthases

机译：站点定向诱变作为精密工具以使合成生物学与工程化的模块化聚酮合成酶
- 作者：Erin E. Drufva;Elijah G. Hix;Constance B. Bailey
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第2期
78.Exploring the molecular basis for selective C–H functionalization in plant P450s

机译：探索植物P450S中选择性C-H官能化的分子基础
- 作者：Rosa V. Espinoza;David H. Sherman
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第2期
79.Designing sgRNAs for CRISPR-BEST base editing applications with CRISPy-web 2.0

机译：使用CRISPY-Web 2.0设计SGRNA用于CRISPR-BEST基础编辑应用程序
- 作者：Kai Blin;Simon Shaw;Yaojun Tong;Tilmann Weber
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第2期
80.A high stable pH-temperature dual-sensitive liposome for tuning anticancer drug release

机译：高稳定的pH - 温度双敏脂质体用于调整抗癌药物释放
- 作者：Yilin Zhao;Fuli Cai;Xiangyi Shen;Haijia Su
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第2期
81.Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways

机译：工程大肠杆菌通过前体和辅因子途径的遗传操作来改善色氨酸生产
- 作者：Zhu Li;Dongqin Ding;Huiying Wang;Linxia Liu;Huan Fang;Tao Chen;Dawei Zhang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
82.Positional assembly of multi-enzyme cascade reaction in polyelectrolyte doped microcapsule through electrospray and layer-by-layer assembly

机译：聚电解质掺杂微胶囊通过电喷雾和逐层组装在聚电解质掺杂微胶囊的位置组装
- 作者：Shiyi Che;Jie Wang;Xiaoyuan Ji;Zhiguo Su;Shaomin Wang;Songping Zhang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
83.Mining and fine-tuning sugar uptake system for titer improvement of milbemycins in Streptomyces bingchenggensis

机译：矿床改善米拉米斯突霉素突发型矿床的开采和微调糖摄取系统
- 作者：Pinjiao Jin;Shanshan Li;Yanyan Zhang;Liyang Chu;Hairong He;Zhuoxu Dong;Wensheng Xiang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
84.Unstructured kinetic models to simulate an arabinose switch that decouples cell growth from metabolite production

机译：非结构化的动力学模型用于模拟阿拉伯糖开关从代谢物生产中脱钩细胞生长
- 作者：Harley Edwards;Peng Xu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
85.Redesigning transcription factor Cre1 for alleviating carbon catabolite repression in Trichoderma reesei

机译：重新设计转录因子Cre1用于缓解Trichoderma Reesei中的碳分解代谢物抑制
- 作者：Lijuan Han;Kuimei Liu;Wei Ma;Yi Jiang;Shaoli Hou;Yinshuang Tan;Quanquan Yuan;Kangle Niu;Xu Fang
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
86.Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 from Sebekia benihana

机译：来自Sebrekia Benihana的环孢菌素A羟化酶CYP-SB21的结构引导的操纵
- 作者：Fengwei Li;Li Ma;Xingwang Zhang;Jingfei Chen;Feifei Qi;Yinyue Huang;Zepeng Qu;Lishan Yao;Wei Zhang;Eung-Soo Kim;Shengying Li
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第3期
87.Enhancing single-cell hyaluronic acid biosynthesis by microbial morphology engineering

机译：通过微生物形态学提高单细胞透明质酸生物合成
- 作者：Yukun Zheng;Fangyu Cheng;Bo Zheng;Huimin Yu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
88.Converting Escherichia coli MG1655 into a chemical overproducer through inactivating defense system against exogenous DNA

机译：通过将防御系统反对外源性DNA将大肠杆菌MG1655转换为化学过度级数。
- 作者：Jingge Wang;Chaoyong Huang;Kai Guo;Lianjie Ma;Xiangyu Meng;Ning Wang;Yi-Xin Huo
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
89.Physical stimuli-responsive cell-free protein synthesis

机译：物理刺激响应无细胞蛋白质合成
- 作者：Junzhu Yang;Yuan Lu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
90.Erratum regarding previously published articles

机译：关于以前公布的文章的错误
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
91.Erratum regarding previously published articles

机译：关于以前公布的文章的错误
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
92.Erratum regarding previously published articles

机译：关于以前公布的文章的错误
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
93.Erratum regarding previously published articles

机译：关于以前公布的文章的错误
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
94.Emerging biosensors in detection of natural products

机译：检测天然产品的新兴生物传感器
- 作者：Firoozeh Piroozmand;Fatemeh Mohammadipanah;Farnoush Faridbod
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
95.Applications of phage-derived RNA-based technologies in synthetic biology

机译：噬菌体衍生RNA技术在合成生物学中的应用
- 作者：Wenhui Zhang;Qiong Wu
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
96.Natural products research in the modern age

机译：现代时代的天然产品研究
- 作者：Yaojun Tong
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
97.Editorial for special issue on green biomanufacturing

机译：关于绿色生物化制造的特殊问题的编辑
- 作者：Yongqin Lv;Haijia Su;Tianwei Tan
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2020年第4期
98.An efficient marker recycling system for sequential gene deletion in a deep sea-derived fungus Acremonium sp. HDN16-126

机译：深海衍生的真菌侵袭性Sp中的顺序基因缺失有效标记回收系统。 HDN16-126.
- 作者：Ruonan Sun;Hengyi Xu;Yanyan Feng;Xuewen Hou;Tianjiao Zhu;Qian Che;Blaine Pfeifer;Guojian Zhang;Dehai Li
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第2期
99.Biodegradation of aromatic pollutants meets synthetic biology

机译：芳香族污染物的生物降解符合合成生物学
- 作者：Liang Xiang;Guoqiang Li;Luan Wen;Cong Su;Yong Liu;Hongzhi Tang;Junbiao Dai
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第3期
100.O-glycosyltransferases from Homo sapiens contributes to the biosynthesis of Glycyrrhetic Acid 3-O-mono-β-D-glucuronide and Glycyrrhizin in Saccharomyces cerevisiae

机译：来自HOMO SAPIENS的O-糖基转移酶有助于甘草酸3-O-MONO-β-D-葡萄糖醛糖苷和糖精酿酒酵母的生物合成
- 作者：Ke Xu;Yu-jia Zhao;Nadeem Ahmad;Jing-nan Wang;Bo Lv;Ying Wang;Jun Ge;Chun Li
- 期刊名称：《Synthetic and Systems Biotechnology》 | 2021年第3期