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Coxiella burnetii lipopolysaccharides: Structural Characterization, Chemical Synthesis and Immunogen Development

机译：Coxiella burnetii脂多糖：结构表征，化学合成和免疫原发展

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Component structures of Coxiella burnetii lipopolysaccharide have been provided for a detailed structural analysis of sequence and branching. Because of the SDS-PAGE electrophoretic simplicity, much effort has been focused on the lipopolysaccharide obtained from phase II. The results indicate a basic core structure consisting of a (1-3)-mannoheptose backbone with every residue (1-2) branched with a single mannose moiety. Lipid C, obtained from LPS-II, (the counterpart of Saimonella lipid A), appears to be quite unusual in that it lacks carbohydrate and is small in molecular weight. Lipopolysaccharide obtained from phase I has indicated some homology with phase II with the same tetrasaccharide. Methods have been developed to examine these structures at greater sensitivity and specificity. Limitations to effective structural conclusions relate to the complications of partial hydrolytic degradations.

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作者
Her, G.; Reinhold, V. N.;
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年度 1986
页码 p.1-34
总页数 34
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Coxiella burnetii; Lipopolysaccharides; Degradation; Hydrolysis; Immunogens; Lipids; Molecular weight; Sequences; Structural analysis; Structural properties; Mass spectrometry;

机译：Coxiella burnetii;脂多糖;降解;水解;免疫原;脂质;分子量;序列;结构分析;结构特性;质谱;

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1. Coxiella burnetii, the causative agent of Q fever in Saudi Arabia：molecular detection from camel and other domestic livestock [J] . Osama B Mohammed, Abdulrahman A Jarelnabi, Riyadh S Aljumaah, 亚太热带医药杂志（英文版） . 2014,第009期
2. Herd-prevalence of Coxiella burnetii (Q fever) antibodies in dairy cattle farms based on bulk tank milk analysis [J] . Mohammad Khalili, Ehsanollah Sakhaee, Mohammad Reza Aflatoonian, 亚太热带医药杂志（英文版） . 2011,第001期
3. Characterizations of Chinese isolates of Coxiella burnetii in the com1 gene sequence [J] . YU Quan, ZHANG Guo-quan, FUKUSHI Hideto, 中国人民解放军军医大学学报（英文版） . 2002,第002期
4. Chemical and immunological characterization of lipopolysaccharides from phase I and phase II Coxiella burnetii. [J] . K Amano, J C Williams Journal of bacteriology . 1984,第3期

机译：I和II期Coxiella burnetii脂多糖的化学和免疫学表征。
5. Further structural characteristics of the lipopolysaccharide from Coxiella burnetii strain Nine Mile in low virulent phase II [J] . Toman R, Hussein A, Slaba K, Acta Virologica: International Journal . 2003,第2期

机译：低毒II期伯氏柯氏杆菌九英里株脂多糖的进一步结构特征
6. STRUCTURAL STUDY ON A LIPOPOLYSACCHARIDE FROM COXIELLA BURNETII STRAIN NINE MILE IN AVIRULENT PHASE II [J] . Toman R., Skultety L. Carbohydrate research . 1996,第0期

机译：剧毒II期鼠尾草9号英里脂多糖的结构研究
7. Synthesis of Na-MnO_2 Electrodes and Its Microstructural and Electrochemical Characterization [C] . Lorena Guadalupe Cuellar Herrera, Jose Antonio Romero Serrano, Elsa Miriam Estrada-Arce Meeting of the Electrochemical Society;International Meeting on Chemical Sensors . 2020

机译：Na-MnO_2电极的合成及其微观结构和电化学表征
8. Characterization of the GDP-D-Mannose Biosynthesis Pathway in Coxiella burnetii: The Initial Steps for GDP-β-D-Virenose Biosynthesis [D] . Narasaki, Craig Toshiro 2010

机译：枯草杆菌中GDP-D-甘露糖生物合成途径的表征：GDP-β-D-维纳糖生物合成的初始步骤
9. Chemical and immunological characterization of lipopolysaccharides from phase I and phase II Coxiella burnetii. [O] . K Amano, J C Williams 1984

机译：一期和二期柯氏杆菌的脂多糖的化学和免疫学表征。
10. Chemical and immunological characterization of lipopolysaccharides from phase I and phase II Coxiella burnetii [O] . K Amano, J C Williams 1984

机译：I和II型Coxiella Burnetii的脂多糖的化学和免疫表征
11. Chemical Synthesis Coxiella Burnetti Lipopolysaccharides: Structural Studies of Coxiella Burnetti Lipopolysaccharides [R] . Her, G. R., Reinhold, V. N. 1987

机译：化学合成Coxiella Burnetti脂多糖：Coxiella Burnetti脂多糖的结构研究

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Coxiella burnetii lipopolysaccharides: Structural Characterization, Chemical Synthesis and Immunogen Development

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