首页> 美国政府科技报告 >Drug Development and Conservation of Biodiversity in West and Central Africa: Performance of Neurochemical and Radio Receptor Assays of Plant Extracts Drug Discovery for the Central Nervous System

【24h】

Drug Development and Conservation of Biodiversity in West and Central Africa: Performance of Neurochemical and Radio Receptor Assays of Plant Extracts Drug Discovery for the Central Nervous System

机译：西非和中非的药物开发和生物多样性保护：中枢神经系统的植物提取物的神经化学和无线电受体分析的发现

获取原文

页面导航

摘要
著录项
相似文献
相关主题

摘要

The thrust of the CNS assay panel was to identify plant extracts that display moderate to high affinity for selected molecular targets. Target selection was based identifying active plant extracts that would be useful for one or more neuropsyschiatric disorders. We completed a screen for 102 samples belonging to 43 plants. 41 showed activity at one or more CNS targets. Phytochemical studies have been initiated on several active extracts. A total of 12 plants samples which have tested positive for antiplasmodial activity were collected in bulk quantities for detailed phytochemical investigations into antimalarial and trypanocidal activity.

著录项

作者
Efange, S. ; Mash, D. C.;
展开▼
作者单位

展开▼
年度 2004
页码 p.1-34
总页数 34
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Drugs; Central nervous system; Neurochemistry; Plants(Botany); West africa; Biological extracts;

机译：药物;中枢神经系统;神经化学;植物（植物学）;西非;生物提取物;

相似文献

外文文献
中文文献
专利

1. Allosteric modulation of seven transmembrane spanning receptors: Theory, practice, and opportunities for central nervous system drug discovery [J] . Melancon B.J., Hopkins C.R., Wood M.R., Journal of Medicinal Chemistry . 2012,第4期

机译：七个跨膜受体的变构调节：理论，实践和中枢神经系统药物发现的机会
2. 5?HT_(1A) Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer [J] . Ferdinando Fiorino, Beatrice Severino, Elisa Magli, Journal of Medicinal Chemistry . 2014,第11期

机译：5？HT_（1A）受体：作为从中枢神经系统到癌症的药物发现的新靶标的古老靶标
3. The development of biomarkers to reduce attrition rate in drug discovery focused on oncology and central nervous system [J] . Safavi Maliheh, Sabourian Reyhaneh, Abdollahi Mohammad Expert opinion on drug discovery . 2016,第10期

机译：在肿瘤学和中枢神经系统中，开发用于降低药物发现中损耗率的生物标志物
4. Fragment-Based Drug Discovery for Diseases of the Central Nervous System [C] . Vicki L Nienaber Symposium on library design, search methods, and applications of fragment-based drug design . 2011

机译：基于片段的中枢神经系统疾病的药物发现
5. Method development and validation for the estimation of certain drugs acting on central nervous system in dosage form and biological matrices by reverse phase high performance liquid chromatography. [D] . Baldania, Sunil L. 2009

机译：反相高效液相色谱法估算某些以剂型和生物基质作用于中枢神经系统的药物的方法开发和验证。
6. ADDME – Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective [O] . Katya Tsaioun, Michel Bottlaender, Aloise Mabondzo 2009

机译：ADDME –尽早避免药物开发错误：中枢神经系统药物发现的观点
7. ADDME – Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective [O] . Mabondzo Aloise, Bottlaender Michel, Tsaioun Katya 2009

机译： ADDME –尽早避免药物开发错误：中枢神经系统药物发现的前景

Drug Development and Conservation of Biodiversity in West and Central Africa: Performance of Neurochemical and Radio Receptor Assays of Plant Extracts Drug Discovery for the Central Nervous System

摘要

著录项

相似文献

相关主题

期刊订阅