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Activity of Imipenem against Klebsiella pneumoniae Biofilms In Vitro and In Vivo.

机译：亚胺培南对肺炎克雷伯菌生物膜体外和体内活性的影响。

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Encapsulated Klebsiella pneumoniae has emerged as one of the most clinically relevant and more frequently encountered opportunistic pathogens in combat wounds as the result of nosocomial infection. In this report, we show that imipenem displayed potent activity against established K. pneumoniae biofilms under both static and flow conditions in vitro. Using a rabbit ear model, we also demonstrated that imipenem was highly effective against preformed K. pneumoniae biofilms in wounds.

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Chen, P.; Seth, A. K.; Abercrombie, J. J.; Mustoe, T. A.; Leung, K. P.;
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年度 2014
页码 1-7
总页数 7
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
ANTIBIOTICS; KLEBSIELLA PNEUMONIAE; WOUNDS AND INJURIES; IN VITRO ANALYSIS; IN VIVO ANALYSIS; KLEBSIELLA PNEUMONIAE BIOFILMS; IMIPENEM; COMBAT WOUNDS;

机译：抗生素; KLEBsIELLa pNEUmONIaE;伤口和受伤;体外分析;体内分析; KLEBsIELLa肺炎生物膜; ImIpENEm; COmBaT WOUNDs;

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1. Activity of imipenem against Klebsiella pneumoniae Biofilms in vitro and in vivo [J] . ChenP., SethA.K., AbercrombieJ.J., Antimicrobial agents and chemotherapy. . 2014,第2期

机译：亚胺培南在体外和体内对肺炎克雷伯菌生物膜的活性
2. i >In vitro/i>In vitro activity of antimicrobial‐impregnated catheters against biofilms formed by KPC‐producing i >Klebsiella pneumoniae/i>Klebsiella pneumoniae [J] . Sousa J.K.T., Haddad J.P.A., Oliveira A.C., Journal of applied microbiology . 2019,第4期

机译：＆ i>在体外体外抗微生物浸渍导管的体外活性，用于通过KPC制备蛋白氏蛋白氏蛋白氏蛋白氏蛋白酶＆ / i>肺炎群岛
3. In vitro activity of imipenem-relebactam against non-MBL carbapenemase-producing Klebsiella pneumoniae isolated in Greek hospitals in 2015-2016 [J] . Galani Irene, Souli Maria, Nafplioti Konstantina, European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology . 2019,第6期

机译：ImipeNem-creebactam对2015-2016的希腊医院孤立的非MBL碳碱酶促蛋白酶菌肺炎的体外活性
4. The antimicrobial activity of photodynamic therapy against Streptococci species in dental biofilm using different photosensitizers: An in vitro study [C] . Spinei Aurelia, Spinei Iurie IEEE International Conference on E-Health and Bioengineering . 2013

机译：使用不同的光敏剂的光动力疗法对牙科生物膜中链球菌物种的抗菌活性：一项体外研究
5. A mechanistic basis for Bordetella biofilm formation: In vitro and in vivo. [D] . Sloan, Gina Parise. 2007

机译：博德特氏菌生物膜形成的机制基础：体外和体内。
6. Activity of Imipenem against Klebsiella pneumoniae Biofilms In Vitro and In Vivo [O] . Ping Chen, Akhil K. Seth, Johnathan J. Abercrombie, 2014

机译：亚胺培南对体外和体内抗肺炎克雷伯菌生物膜的活性

Activity of Imipenem against Klebsiella pneumoniae Biofilms In Vitro and In Vivo.

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