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Effects of Morphine Sulfate on Agglutination, Clot Formation and Hemolysis in Packed Red Blood Cells

机译:硫酸吗啡对包装红细胞凝集,凝块形成和溶血的影响

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Morphine sulfate is an opium alkaloid narcotic frequently used on patients suffering from acute and chronic disease processes. Often patients receiving either acute or long- term pain therapy with morphine require concomitant blood transfusion therapy. Based on current American Association of Blood Banks guidelines the addition of any medication other than normal saline to packed red blood cells is strictly prohibited. This restriction can lead to unwanted delays in medication schemes when patients with limited intravenous access are in need of both therapies at the same time. Few studies exist that have investigated the effects of morphine sulfate on packed red blood cells. Most of these have, in a limited manner, presented contrasting evidence on the efficacy of this practice.

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