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Bench-scale co-oxidative production of propylene oxide by methanotrophs

机译：通过甲烷氧化物的大规模共氧化生产环氧丙烷

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The feasibility of the co-oxidative production of value-added chemicals using methanotrophs has been investigated by the authors. Several of these co-oxidative products have been evaluated for stereo- or regiospecific properties. Propylene oxide (1,2-epoxypropane) is one of the products that has been selected for further evaluation. This paper describes the first steps toward bench-scale production of propylene oxide. Propylene oxide has been produced stereospecifically (60% R-form, 40% S-form) in gram quantities in bench-scale liquid culture reactors. Several operational parameters and conditions have been determined for both a continuous stirred-tank reactor (CSTR) and a packed-bed bubble-column reactor (PBR). The production phase of the propylene oxide has been significantly extended by intermittent addition of propylene and regeneration with methane. The paper also describes the performance of the CSTR and PBR for propylene oxide production.

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