首页> 美国政府科技报告 >Identification of Proteins and Formed Elements Deposited During Dialysis. Significance of Adsorption and Orientation of Proteins to Platelet and White Cell Deposition.
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Identification of Proteins and Formed Elements Deposited During Dialysis. Significance of Adsorption and Orientation of Proteins to Platelet and White Cell Deposition.

机译:透析过程中沉积的蛋白质和成形元素的鉴定。蛋白质吸附和取向对血小板和白细胞沉积的意义。

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During dialysis onto cuprophane and nylon filters, neutrophil leukocytes are deposited mainly,but onto polyacrylonitrile membrane,few formed elements appear to adhere. Little clotting activity,but some evidence of fibrinogen and gamma globulin adsorption was found on cuprophane after dialysis,while unused polyacrylonitrile appeared to adsorb more fibrinogen than did cuprophane upon brief exposure to normal plasmas. Studies on ultrafiltration and exposure time have begun with a test dialyzer providing controlled flow. In other work,gamma globulin adsorbed onto hydrophobic surfaces caused granulocyte adhesion;adsorbed onto hydrophilic surfaces it did not,unless dried once,paralleling the behavior of fibrinogen and its effect on platelet adhesion.

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