• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文OA文献 >The contribution of pre-existing depression to the acute cognitive sequelae of mild traumatic brain injury
【2h】

The contribution of pre-existing depression to the acute cognitive sequelae of mild traumatic brain injury

机译：预先存在抑郁症对轻度创伤性脑损伤的急性认知后遗症的贡献

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Frontotemporal abnormalities and cognitive dysfunction, especially in verbal memory and information processing speed, occur in both mild traumatic brain injury (mTBI) and depression. Study 1 investigated the effect of depression on cognitive performance in a sample at risk of sustaining mTBI.Seventy-eight male undergraduates completed the Depression Anxiety Stress Scales (DASS), Digit Symbol Substitution Test (DSS), Hopkins Verbal Learning Test (HVLT), and Speed of Comprehension Test. A oneway analysis of covariance (using the top 25% and bottom 25% of DASS Depression subscale scorers) showed that HVLT recognition was significantly worse in the high scorers. Study 2 examined the effects of injury type and pre-existing depression on cognitive performance in a prospective emergency department sample (within 24 hours of injury). Fifty-eight participants with mTBI (29 with depression, 29 without depression) and 47 control participants (18 with depression, 29 without depression) completed the DSS, HVLT, and Speed of Comprehension Test. Participants with mTBI performed worse than controls (uninjured and orthopaedic-injured participants) on all tests. Participants with depression did not perform worse than participants without depression on the tests. However, there was a significant univariate interaction for HVLT recognition, participants in the mTBI group with depression exhibited worse recognition compared to participants without depression. Since word recognition was impaired in participants who were more depressed in both samples, this suggests that it is a consistent finding. More importantly, the results of Study 2 indicate that depression may interact with mTBI to impair word recognition during the acute phase after head injury.
机译：额颞异常和认知功能障碍，特别是在口头记忆和信息处理速度方面，在轻度创伤性脑损伤（mTBI）和抑郁症中均会发生。研究1研究了抑郁症对维持mTBI风险的样本中认知能力的影响.88名男大学生完成了抑郁焦虑量表（DASS），数字符号替代测验（DSS），霍普金斯语言学习测验（HVLT），和理解测试的速度。对协方差的单向分析（使用DASS抑郁量表的前25％和后25％的得分者）显示，在高得分者中HVLT识别明显较差。研究2在预期的急诊科样本中（受伤后24小时内）检查了伤害类型和既往抑郁症对认知能力的影响。 58名患有mTBI的参与者（29名有抑郁症，29名无抑郁症）和47名对照参与者（18名有抑郁症，29名无抑郁症）完成了DSS，HVLT和理解速度测试。在所有测试中，mTBI参与者的表现均比对照组（未受伤和骨科受伤的参与者）差。患有抑郁症的参与者的表现没有比没有抑郁症的参与者的表现差。但是，HVLT识别存在显着的单变量交互作用，与没有抑郁的参与者相比，患有抑郁症的mTBI组的参与者表现出更差的识别能力。由于在两个样本中都比较沮丧的参与者的单词识别能力受损，因此这表明这是一个一致的发现。更重要的是，研究2的结果表明，在颅脑损伤后的急性期，抑郁症可能与mTBI相互作用，从而削弱了单词识别能力。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号