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首页> 外文OA文献 >The effects of hormone replacement therapy on mammographic density among postmenopausal women in Hospital Raja Perempuan Zainab Ii, Kota Bharu, Kelantan.
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The effects of hormone replacement therapy on mammographic density among postmenopausal women in Hospital Raja Perempuan Zainab Ii, Kota Bharu, Kelantan.

机译：吉兰丹州哥打巴鲁Zainab Ii医院激素替代疗法对绝经后妇女乳房X线照片密度的影响。

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Introduction Hormone replacement therapy (HRT) is commonly prescribed to postmenopausal women to improve their postmenopausal symptoms. Postmenopausal hormone use is associated with increase in mammographic density and increased incidence of breast pain. Mammographic density is an independent risk factor for breast cancer. Objective Our purpose was to evaluate the effects of hormone replacement therapy on mammographic density in postmenopausal women in Kota Bharu, Kelantan, Malaysia. Material and Method An observational study was conducted for a period of 18 months. A total of 33 postmenopausal women who received combined hormone replacement therapy (containing estrogen and progesterone) were included as study subjects. Mammograms were performed at baseline and after 12 months of receiving HRT. Mammographic density was evaluated according to BIRADS classification of breast density. During follow-up, patients were also enquired about breast pain and they were asked to classify according to a specified scale. Result The categorical assessments showed that there was a significant shift in categorical classification as assessed by BIRADS categories among the postmenopausal women receiving hormone replacement therapy. Amongst these women, 30.3% had increased mammographic density after treatment with HRT. There was also significant xiv association between breast pain and increase in mammographic density. Amongst the study population, 33.3% complained of breast pain after hormonal therapy. We also concluded that the study factors (grade, age, parity, BMI, duration of menopause and age at menopause) did not significantly influence change in mammographic density. Conclusion Hormone replacement therapy significantly affects the mammographic density and increased mammographic density was associated with breast pain in women receiving hormonal therapy.
机译：简介激素替代疗法（HRT）通常用于绝经后女性，以改善其绝经后症状。绝经后激素的使用与乳房X线照片密度的增加和乳房疼痛的发生率增加有关。乳房X线照片密度是乳腺癌的独立危险因素。目的我们的目的是评估激素替代疗法对马来西亚吉兰丹州哥打巴鲁市绝经后妇女的乳房X线照片密度的影响。材料和方法进行了为期18个月的观察性研究。总共33名接受联合激素替代疗法（包含雌激素和孕激素）的绝经后妇女被纳入研究对象。在基线和接受HRT治疗12个月后进行乳房X光检查。根据BIRADS对乳房密度的分类来评估乳房X线照片的密度。在随访期间，还询问患者乳房疼痛的情况，并要求他们根据指定的等级进行分类。结果分类评估显示，按BIRADS类别评估，绝经后接受激素替代治疗的女性的分类明显改变。在这些妇女中，接受HRT治疗后的乳房X线照片密度增加了30.3％。乳房疼痛与乳房X线照片密度增加之间也存在显着的xiv关联。在研究人群中，有33.3％的人抱怨激素治疗后出现乳房疼痛。我们还得出结论，研究因素（等级，年龄，均等，BMI，绝经持续时间和绝经年龄）不会显着影响乳房X线照片密度的变化。结论激素替代治疗显着影响乳房X线照片密度，而乳房X线照片密度增加与接受激素治疗的妇女的乳房疼痛有关。

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    Kamaravel Shanti;

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  • 年度 2011
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