Breast density changes associated with hormone replacement therapy in postmenopausal women. Effects on the specificity and sensitivity of mammographic screening.

Patella A; Marziani R; Schippa A; Benedetti S; Mossa S; Mossa B

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Breast density changes associated with hormone replacement therapy in postmenopausal women. Effects on the specificity and sensitivity of mammographic screening.

机译：绝经后妇女与激素替代疗法相关的乳房密度变化。对乳腺X线摄影筛查的特异性和敏感性的影响。

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摘要

Postmenopausal HRT use is associated with an increase of mammographic density and reduction of sensitivity and specificity of mammography results and an increase of false-positive and false-negative outcomes. The increased density does not allow a good evaluation of the exam. Mammographic density is an independent risk factor for breast cancer, but the link between changes in breast density and difference in breast cancer risk, remain uncertain. On the other hand, today specific guidelines and protocols to optimize the screening of neoplastic breast pathology in HRT users do not exist and it is unknown if short-term suspension of therapy improves mammographic sensitivity. More information is required to define this important risk factor.

机译：绝经后HRT的使用与乳房X线照片密度的增加以及乳房X线照片结果的敏感性和特异性的降低以及假阳性和假阴性结果的增加相关。增加的密度不允许对检查进行良好的评估。乳房X线照片密度是乳腺癌的独立危险因素，但是乳房密度变化与乳腺癌风险差异之间的联系仍然不确定。另一方面，目前尚不存在用于优化HRT使用者乳腺肿瘤病理筛查的具体指南和协议，并且短期中止治疗是否可以提高乳房X线照片的敏感性尚不得而知。需要更多信息来定义此重要风险因素。

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来源
《European journal of gynaecological oncology》 |2005年第5期|共6页
作者
Patella A; Marziani R; Schippa A; Benedetti S; Mossa S; Mossa B;
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正文语种 eng
中图分类妇产科学;
关键词
physical density; Hormone Replacement Therapy; Aspects of disease screening; 激素替代疗法;

机译：physical density;Hormone Replacement Therapy;Aspects of disease screening;激素替代疗法;

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专利

1. Breast density changes associated with hormone replacement therapy in postmenopausal women. Effects on the specificity and sensitivity of mammographic screening. [J] . Patella A, Marziani R, Schippa A, European journal of gynaecological oncology . 2005,第5期

机译：绝经后妇女与激素替代疗法相关的乳房密度变化。对乳腺X线摄影筛查的特异性和敏感性的影响。
2. Effects of hormone replacement therapy on the phospholipid composition of high density lipoproteins in postmenopausal women. [J] . Papapanagiotou A, Koufali MM, Zachari A, Journal of obstetrics and gynaecology: the journal of the Institute of Obstetrics and Gynaecology . 2001,第1期

机译：激素替代疗法对绝经后妇女高密度脂蛋白磷脂成分的影响。
3. Relationships between circulating hormone levels, mammographic percent density and breast cancer risk factors in postmenopausal women. [J] . Johansson H, Gandini S, Bonanni B, Breast cancer research and treatment. . 2008,第1期

机译：绝经后妇女循环激素水平，乳房X线照片密度和乳腺癌危险因素之间的关系。
4. Hormone replacement therapy andatherosclerosis-postmenopausal women and HRT:the fallen myth of the cardiovascular protectiveeffects of hormone replacement therapy [C] . Emilio H. Moriguchi, Jose Luiz C. Vieira International Symposium on Atherosclerosis . 2004

机译：激素替代治疗和动脉粥样硬化 - 绝经后妇女和HRT：激素替代治疗心血管保护作用的下降神话
5. The association of endogenous pineal hormone melatonin and mammographic breast density in postmenopausal women. [D] . Teter, Barbara Elizabeth. 2007

机译：绝经后妇女内源性松果激素褪黑激素与乳房X线照片的乳房密度的关系。
6. Hormone replacement therapy percent mammographic density and the sensitivity of mammography [O] . AM Kavanagh, JN Cawson, GB Byrnes, 2004

机译：激素替代疗法乳腺X射线摄影密度百分比和乳腺X射线摄影敏感性
7. The effects of hormone replacement therapy on mammographic density among postmenopausal women in Hospital Raja Perempuan Zainab Ii, Kota Bharu, Kelantan. [O] . Kamaravel Shanti 2011

机译：吉兰丹州哥打巴鲁Zainab Ii医院激素替代疗法对绝经后妇女乳房X线照片密度的影响。
8. Increasing Mammographic Breast Density in Response to Hormone Replacement Therapy and Breast Cancer Risk [R] . Harvey, J. A. 2003

机译：增加乳腺摄影乳腺密度以响应激素替代疗法和乳腺癌风险

Breast density changes associated with hormone replacement therapy in postmenopausal women. Effects on the specificity and sensitivity of mammographic screening.

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