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HMGB1 A method for pathogenesis prediction to kawasaki disease using the HMGB1 genes SNP
HMGB1 A method for pathogenesis prediction to kawasaki disease using the HMGB1 genes SNP
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机译：HMGB1一种使用HMGB1基因SNP预测川崎病发病机理的方法
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摘要
The present invention relates to a method for predicting Kawasaki disease symptoms using HMGB1 gene polymorphism. Kawasaki disease is an acute febrile rash that occurs mainly in infants under five years of age, and coronary artery lesions can develop without proper use of intravenous immunoglobulin (IVIG). However, intravenous immunoglobulin resistance often occurs in patients with Kawasaki disease, which is difficult to treat. Kawasaki disease symptom prediction method using the HMGB1 gene polymorphism of the present invention to determine the association between the HMGB1 gene and Kawasaki disease symptoms, the possibility of the formation of coronary artery lesions or intravenous immunoglobulin resistance in patients with Kawasaki disease As it is predictable in advance, it is expected to be widely used in the medical field.
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