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THERAPEUTIC AND PROPHYLACTIC AGENT FOR GLIOMA, BRAIN TUMOR MALIGNANCY MARKER, BRAIN TUMOR PROGNOSTIC MARKER, METHOD FOR DETERMINING MALIGNANCY AND PROGNOSIS OF BRAIN TUMOR AND ANTIBODY INHIBITING TUMOR PROLIFERATION
THERAPEUTIC AND PROPHYLACTIC AGENT FOR GLIOMA, BRAIN TUMOR MALIGNANCY MARKER, BRAIN TUMOR PROGNOSTIC MARKER, METHOD FOR DETERMINING MALIGNANCY AND PROGNOSIS OF BRAIN TUMOR AND ANTIBODY INHIBITING TUMOR PROLIFERATION
The purpose of the present invention is to provide a novel therapeutic or prophylactic agent for a glioma, a brain tumor malignancy marker, a brain tumor prognostic marker, a method for determining the malignancy of a brain tumor, and a method for determining the prognosis of a brain tumor patient. According to the present invention, provided are: a therapeutic and prophylactic agent for a glioma, said agent containing an HVEM inhibitor as an active ingredient; a brain tumor malignancy marker and a brain tumor prognostic marker, each marker comprising an HVEM protein or an HVEM gene; and a method for determining the malignancy of a brain tumor and a method for determining the prognosis of a brain tumor patient, each method comprising a step for measuring the HVEM expression level in a biological sample collected from a subject.
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