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THERAPEUTIC AND PROPHYLACTIC AGENT FOR GLIOMA, BRAIN TUMOR MALIGNANCY MARKER, BRAIN TUMOR PROGNOSTIC MARKER, METHOD FOR DETERMINING MALIGNANCY AND PROGNOSIS OF BRAIN TUMOR AND ANTIBODY INHIBITING TUMOR PROLIFERATION
THERAPEUTIC AND PROPHYLACTIC AGENT FOR GLIOMA, BRAIN TUMOR MALIGNANCY MARKER, BRAIN TUMOR PROGNOSTIC MARKER, METHOD FOR DETERMINING MALIGNANCY AND PROGNOSIS OF BRAIN TUMOR AND ANTIBODY INHIBITING TUMOR PROLIFERATION
An object of the present invention is to provide a novel agent for treating or preventing a glioma, to provide a marker for malignancy of a brain tumor and a prognostic marker for a brain tumor, and to provide a method for determining malignancy of a brain tumor and a method for determining a prognosis for a brain tumor patient. According to the present invention, there are provided an agent for treating or preventing a glioma comprising an HVEM inhibitor as an active ingredient; a marker for malignancy of a brain tumor and a prognostic marker for a brain tumor, each comprising an HVEM protein or an HVEM gene; and a method for determining malignancy of a brain tumor and a method for determining a prognosis for a brain tumor patient, each comprising measuring an HVEM expression amount in a biological sample of a subject.
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