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RUBBERY, COMPLIANT, AND SUTURABLE COLLAGEN-BASED SCAFFOLDS FOR TISSUE ENGINEERING APPLICATIONS
RUBBERY, COMPLIANT, AND SUTURABLE COLLAGEN-BASED SCAFFOLDS FOR TISSUE ENGINEERING APPLICATIONS
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机译:面向组织工程应用的基于橡胶的,可兼容的和可固化的基于胶原的支架
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摘要
A collagen-based or gelatin-based formulation that is compliant yet strong and has a high suture-strength value is disclosed. This material is simple to synthesize, behaves like a rubbery material, and is the first type of solely collagen-based compliant material without using elastin. The formulation maintains the strength of collagen, but can be stretched to several times its initial dimension and can be sutured without leaking. The suture retention strength can reach up to 350-grams force. The presently disclosed collagen-based formulation can be used in variety of applications where high strength, compliance, or stretchability is required, such as in urinary tissues, intestinal tissues, heart tissues, and skin.
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