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Substituted (4'-hydroxyphenyl) cycloalkane and (4'-hydroxyphenyl) cycloalkene compounds and methods of their use as selective agonists of estrogen receptor beta isoforms to improve memory consolidation
Substituted (4'-hydroxyphenyl) cycloalkane and (4'-hydroxyphenyl) cycloalkene compounds and methods of their use as selective agonists of estrogen receptor beta isoforms to improve memory consolidation
Disclosed are substituted (4'-hydroxyphenyl) cycloalkane compounds and substituted (4'-hydroxyphenyl) cycloalkene compounds and methods of their use as selective agonists of the estrogen receptor beta isoform (ERβ). The disclosed compounds may be formulated as a pharmaceutical composition, wherein diseases associated with ER activity, such as neurological and neurological disorders, psychiatric and psychiatric disorders and / or cell proliferation. To treat sexual disorders and cell proliferative disorders, as well as to improve memory consolidation, in subjects in need.
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