首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR TREATING ORAL PRECANCER AND METHOD FOR PREDICTING OR DIAGNOSING ORAL PRECANCER OR ORAL CANCER

PHARMACEUTICAL COMPOSITION FOR TREATING ORAL PRECANCER AND METHOD FOR PREDICTING OR DIAGNOSING ORAL PRECANCER OR ORAL CANCER

机译:用于治疗口腔癌的药物组合物以及用于预测或诊断口腔癌或口腔癌的方法

摘要

The present invention relates to: a method for providing information for the prediction or diagnosis of oral precancer or oral cancer characterized by confirming expression of the Axin2 gene or the Snail gene in an oral leukoplakia tissue sample or an oral submucous fibrosis tissue sample; and a use of a compound capable of delaying or inhibiting the progression of a precancerous lesion and recurrent oral cancer using the compound capable of effectively inhibiting the expression of the Axin2 gene or the Snail gene. According to the present invention, the possibility of oral leukoplakia or submucous fibrosis which causes white lesions to appear inside the oral cavity can be predicted and diagnosed, thereby being useful in eliminating the potential risks of oral cancer by early prediction of progression into oral precancer or oral cancer for which effective treatment does not currently exist.
机译:本发明涉及提供用于预测或诊断口腔癌前或口腔癌的信息的方法,其特征在于确认口腔白斑组织样品或口腔粘膜下纤维化组织样品中Axin2基因或Snail基因的表达。能够有效地抑制Axin2基因或Snail基因的表达的化合物在能够延迟或抑制癌前病变和复发性口腔癌的进展的化合物中的应用。根据本发明,可以预测和诊断引起口腔内出现白色病变的口腔白斑或粘膜下纤维化的可能性,从而通过早期预测发展为口腔癌前期或口腔癌的可能性来消除口腔癌的潜在风险。目前尚无有效治疗方法的口腔癌。

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