首页> 外国专利> A BIOMATERIAL SCAFFOLD FOR REGENERATING THE ORAL MUCOSA

A BIOMATERIAL SCAFFOLD FOR REGENERATING THE ORAL MUCOSA

机译:一种用于再生口腔粘膜的生物材料支架

摘要

The present invention refers to a process for preparing a biomaterial scaffold said method comprising, (a) providing a hydrogel comprising a fibrin network and a polysaccharide network; (b) optionally, subjecting the hydrogel of step a) to a freeze-thawing process to physically crosslink the hydrogel; and (c) subjecting the hydrogel provided in step a), or the physically cross-linked hydrogel obtained after conducting the step b), to a lyophilization. The invention also relates to the biomaterial scaffold obtainable by the process as defined above, as well said biomaterial scaffold for its use to partially or completely increase, restore or replace the functional activity of a diseased or damaged oral mucosa.
机译:本发明涉及一种用于制备生物材料支架的方法,所述方法包括:(a)提供包含纤维蛋白网络和多糖网络的水凝胶; (b)任选地,使步骤a)的水凝胶经受冻融过程以使水凝胶物理交联; (c)将步骤a)中提供的水凝胶或进行步骤b)后获得的物理交联的水凝胶进行冻干。本发明还涉及可通过上述方法获得的生物材料支架,以及所述生物材料支架,其用于部分或完全增加,恢复或替代患病或受损的口腔粘膜的功能活性。

著录项

  • 公开/公告号EP3209341B1

    专利类型

  • 公开/公告日2020-01-01

    原文格式PDF

  • 申请/专利权人 HISTOCELL S.L.;

    申请/专利号EP20150784393

  • 发明设计人 CASTRO FEO BEGOÑA;BAIGET ORTS AMPARO;

    申请日2015-10-23

  • 分类号A61L27/26;A61L27/56;A61L27/38;A61L27/52;

  • 国家 EP

  • 入库时间 2022-08-21 11:41:59

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