The invention relates to the use of a compound of formula; ;or a pharmaceutically acceptable salt thereof for treating diseases or conditions mediated by Kynurenine 3-monooxygenase activity. These diseases and conditions include neurodegenerative diseases, spinocerebellar ataxias, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, ischemic disorder, acute necrotizing pancreatitis, inflammation, transplant rejection, etc.
展开▼
机译：本发明涉及下式化合物的用途： <图像文件=“ IMGA0002.GIF” he =“ 24” imgContent =“绘图” imgFormat =“ GIF” wi =“ 57” /> ;或其药学上可接受的盐，用于治疗由Kynurenine 3-单加氧酶活性介导的疾病或病症。这些疾病和状况包括神经退行性疾病，脊髓小脑共济失调，阿尔茨海默氏病，帕金森氏病，肌萎缩性侧索硬化症，缺血性疾病，急性坏死性胰腺炎，炎症，移植排斥等。
展开▼
