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Method of producing high functional suture coated with hyaluronate and high functional suture produced thereby
Method of producing high functional suture coated with hyaluronate and high functional suture produced thereby
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机译：透明质酸盐包被的高功能缝合线的制造方法以及由此产生的高功能缝合线
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摘要
This invention relates to a method of manufacturing a hyaluronate-coated high-functional suture and a high-functional suture manufactured thereby, and more particularly to a method of manufacturing a high-functional suture and a high-functional suture manufactured thereby, wherein a suture for internal and external surgery derived from a conventional chemical synthetic material is coated with a hyaluronate as a biocompatible material, thus improving biocompatibility, functionality and ease of use. The method of manufacturing the hyaluronate-coated suture includes (a) preparing a hyaluronate organic-solvent aqueous solution having an organic solvent concentration of 50 ˆ¼ 70 vol% and a hyaluronate concentration of 0.5 ˆ¼ 2 vol% by dissolving a hyaluronate in purified water and then adding an organic solvent thereto, and (b) coating a suture with the hyaluronate organic-solvent aqueous solution and drying the suture. Upon application of the hyaluronate-coated suture of the invention to the human body, the hyaluronate applied on the surface of the suture is rapidly swollen by body fluids and can thus function as a lubricant, thus being convenient to use by a surgical doctor and reducing the pain of a patient and maximizing the functions of skin filling or skin regeneration in the body.
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