首页> 外国专利> COMPOSITIONS AND METHODS RELATED TO ANTIBODIES THAT NEUTRALIZE COAGULASE ACTIVITY DURING STAPHYLOCOCCUS AUREUS DISEASE

COMPOSITIONS AND METHODS RELATED TO ANTIBODIES THAT NEUTRALIZE COAGULASE ACTIVITY DURING STAPHYLOCOCCUS AUREUS DISEASE

机译：在金黄色葡萄球菌病期间中和凝固酶活性中和的与抗原有关的组合物和方法

页面导航

摘要
著录项
相似文献

摘要

Embodiments concern methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. Aspects include methods and compositions for providing a passive immune response against the bacteria. In certain embodiments, the methods and compositions involve an antibody that binds Coagulase (Coa). Further aspects relate to immunogenic compositions comprising at least one Staphylococcal coagulase R Domain, wherein the R Domain is 80% identical in sequence to a R Domain.

机译：实施方案涉及用于治疗或预防细菌感染，特别是葡萄球菌感染的方法和组合物。方面包括用于提供针对细菌的被动免疫应答的方法和组合物。在某些实施方案中，所述方法和组合物涉及结合凝固酶（Coaulase）的抗体。其他方面涉及包含至少一个葡萄球菌凝固酶R结构域的免疫原性组合物，其中所述R结构域与R结构域序列上80％相同。

著录项

公开/公告号EP3416979A4

专利类型
公开/公告日2019-09-11

原文格式PDF
申请/专利权人 THE UNIVERSITY OF CHICAGO;JANSSEN PHARMACEUTICALS INC.;
展开▼

申请/专利号EP20170749960
发明设计人 MISSIAKAS DOMINIQUE;SCHNEEWIND OLAF;EMOLO CARLA;THOMER LENA;MCADOW MOLLY;GEURTSEN JEROEN;DE BEEN MARK;
展开▼

申请日2017-02-10
分类号C07K14/31;A61P31/04;A61K39/395;A61K38/17;C07K16/12;A61K39/085;A61K39/40;C07K16/40;C12Q1/689;A61K39;
国家 EP
入库时间 2022-08-21 12:30:37

相似文献

专利
外文文献
中文文献