首页> 外国专利> Method for preparing colorectal cancer cell line with anticancer drug resistance induced by ribosome-inactivating stress and method for screening inhibitors against anticancer drug resistance of colorectal cancer patients using the same

Method for preparing colorectal cancer cell line with anticancer drug resistance induced by ribosome-inactivating stress and method for screening inhibitors against anticancer drug resistance of colorectal cancer patients using the same

机译:核糖体失活应激诱导的具有抗癌药耐药性的结直肠癌细胞系的制备方法及使用该方法筛选结直肠癌患者抗癌药抑制剂的方法

摘要

The present invention relates to a method for producing a ribosome-inhibiting stress-induced anticancer drug resistant colorectal cancer cell line and a method for screening an anticancer drug resistance-inhibiting agent for a colon cancer patient using the same, wherein the cancer cell exposed to the ribosome-And the sensitivity to the anticancer drug was deteriorated. It is anticipated that the potential resistance effect of anticancer drugs in anticancer therapy for colon cancer can be considered in advance and it will help to establish economical and effective anticancer therapy strategy while overcoming the problems of existing anticancer therapy.;
机译:本发明涉及一种抑制核糖体的应激诱导的抗癌药耐药的结直肠癌细胞系的生产方法,以及使用该方法筛选结肠癌患者的抗癌药的抑制剂的方法,其中所述癌细胞暴露于核糖体-并且抗癌药的敏感性下降。预期可以预先考虑抗癌药在结肠癌抗癌治疗中的潜在耐药性,这将有助于建立经济有效的抗癌治疗策略,同时克服现有抗癌治疗的问题。

著录项

  • 公开/公告号KR101816593B1

    专利类型

  • 公开/公告日2018-01-10

    原文格式PDF

  • 申请/专利权人 부산대학교 산학협력단;

    申请/专利号KR20160026309

  • 发明设计人 문유석;오창규;이승준;

    申请日2016-03-04

  • 分类号C12N5/09;C12N15/01;C12Q1/68;G01N33/50;G01N33/574;

  • 国家 KR

  • 入库时间 2022-08-21 12:38:36

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