COMPOSITIONS AND METHODS SPECIFICALLY TARGETING THE APOLIPOPROTEIN E4 (APOE4) AND USES THEREOF IN APOE4 ASSOCIATED CONDITIONS

• 1. 用于治疗APOE4/4相关病症的方法 [P] . 中国专利： CN112367970A . 2021-02-12
• 2. 表达人APOE4和小鼠Trem2 p.R47H的遗传修饰小鼠及其使用方法 [P] . 中国专利： CN110891417A . 2020-03-17
• 3. COMPOSITIONS AND METHODS SPECIFICALLY TARGETING THE APOLIPOPROTEIN E4 (APOE4) AND USES THEREOF IN APOE4 ASSOCIATED CONDITIONS [P] . 美国专利： US2020046853A1 . 2020-02-13

  机译： 特定针对载脂蛋白E4（APOE4）的组合物和方法，及其在APOE4相关条件下的使用

• 4. COMPOSITIONS AND METHODS SPECIFICALLY TARGETING THE APOLIPOPROTEIN E4 (APOE4) AND USES THEREOF IN APOE4 ASSOCIATED CONDITIONS [P] . 欧洲知识产权局专利： EP3600449A1 . 2020-02-05

  机译： 特定针对载脂蛋白E4（APOE4）的组合物和方法，及其在APOE4相关条件下的使用

• 5. Compositions and methods of targeting apolipoprotein B for the reduction of apolipoprotein C-III [P] . 美国专利： US9107933B2 . 2015-08-18

  机译： 靶向载脂蛋白B以减少载脂蛋白C-III的组合物和方法

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• 2. Sex,ApoE4 and Alzheimer's disease:rethinking drug discovery in the era of precision medicine [J] . Manish D.Paranjpe, Jason K Wang, Yun Zhou 中国神经再生研究（英文版） . 2021,第009期
• 3. Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer [J] . Petros Andrew M., Korepanova Alla, Jakob Clarissa G., Journal of Medicinal Chemistry . 2019,第8期
• 4. Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk varianta??Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUi006-A) - ScienceDirect [J] . Nicholas Brookhouser, Ping Zhang, Richard Caselli, Stem cell research . 2018,第2期
• 5. Generation and characterization of human induced pluripotent stem cell (hiPSC) lines from an Alzheimer's disease (ASUi001-A) and non-demented control (ASUi002-A) patient homozygous for the Apolipoprotein e4 (APOE4) risk variant - ScienceDirect [J] . Nicholas Brookhouser, Ping Zhang, Richard Caselli, Stem cell research . 2017,第2期
• 6. Altered small-world anatomical networks in Apolipoprotein-E4 (ApoE4) carriers using MRI [C] . Goryawala Mohammed, Zhou Qi, Duara Ranjan, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2014
• 7. ApoE4 and the Clinical Outcomes and Pathophysiology of Degenerative Cervical Myelopathy: Evidence from Human Data and Mouse Models [D] . Desimone, Alexa. 2021
• 8. Fatty Acid Binding Protein 3 (FABP3) and Apolipoprotein E4 (ApoE4) as Lipid Metabolism-Related Biomarkers of Alzheimer’s Disease [O] . Maciej Dulewicz, Agnieszka Kulczyńska-Przybik, Agnieszka Słowik, 2021
• 9. Generation and characterization of human induced pluripotent stem cell (hiPSC) lines from an Alzheimer's disease (ASUi001-A) and non-demented control (ASUi002-A) patient homozygous for the Apolipoprotein e4 (APOE4) risk variant [O] . Nicholas Brookhouser, Ping Zhang, Richard Caselli, 2017
• 10. Identification of Novel Therapeutic Targets for Traumatic Brain Injury by Proteomic Analysis of Response to Injury in APOE3 and APOE4 Transgenic Mice [R] . Wood, M., Mouzon, B., Reed, J., 2008

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