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fgf2 binding peptide, fused or conjugated chimeric peptide, nucleic acid molecule, expression vector, host cell and pharmaceutical composition

机译:fgf2结合肽,融合或缀合的嵌合肽,核酸分子,表达载体,宿主细胞和药物组合物

摘要

fgf-2 binding peptides and uses thereof The present invention relates to fgf2 binding peptides are described herein, which were designed from the n-terminal region of ptx3, in particular encompassing the ptx3 region (82). -1 10). Synthetic peptides related to this sequence are able to bind fgf2 and inhibit its pro-angiogenic activity in vitro and in vivo without anticipated impact on innate immunity.
机译:fgf-2结合肽及其用途本发明涉及本文所述的fgf2结合肽,其是从ptx3的n-末端区域设计的,特别是包括ptx3区域的(82)。 -1 10)。与该序列相关的合成肽能够在体外和体内结合fgf2并抑制其促血管生成活性,而不会影响先天免疫。

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