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'anticancer combinations of artemisinin-based drugs and other chemotherapeutic agents'

机译:“基于青蒿素的药物和其他化学治疗剂的抗癌组合”

摘要

"anticancer combinations of artemisinin-based drugs and other chemotherapeutic agents". The present invention relates to combinations of potent artemisinin-based antimalarial agents selected from the group consisting of art, dha and arm, and an additional chemotherapeutic drug selecting from the group consisting of a camptothecin derivative, or a parp-1, or a DNA intercalating agent or an alkylating agent. Such combinations showed medium to strong synergism in several cancer models, especially in the nscl.
机译:“基于青蒿素的药物和其他化学治疗剂的抗癌组合”。本发明涉及选自青蒿素,dha和arm的有效的基于青蒿素的抗疟剂与选自喜树碱衍生物或parp-1或DNA插层的另外的化学治疗药物的组合。剂或烷化剂。这种组合在几种癌症模型中表现出中等至强的协同作用,尤其是在nscl中。

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