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Combined Tandem Mass Spectrometry and Ion Mobility Mass Spectrometry
Combined Tandem Mass Spectrometry and Ion Mobility Mass Spectrometry
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机译：串联质谱和离子淌度质谱
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摘要
A method of analysing ions is disclosed comprising performing an initial multi-dimensional survey scan comprising separating parent ions according to a first physico-chemical property and separating the parent ions according to a second physico-chemical property. At least one parent ion of interest from the initial multi-dimensional survey scan is determined, the at least one parent ion of interest having a first value or range of the first physico-chemical property and a second value or range of the second physico-chemical property. Then, during a subsequent single cycle of separation, the method further comprises separating parent ions according to the first physico-chemical property. If the parent ions have a value or range of the first physico-chemical property which corresponds with the first value or range, then the method further comprises selecting parent ions of interest having a value or range of the first physico-chemical property which corresponds with the first value or range and which also have a value or range of the second physico-chemical property which corresponds with the second value or range. If the parent ions have a value or range of the first physico-chemical property which does not correspond with the first value or range then the method further comprises separating the parent ions according to the first physico-chemical property and separating the parent ions according to the second physico-chemical property.
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