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METHOD FOR PREDICTION OF DEGREE OF RISK OF POLYCYSTIC OVARIAN SYNDROME FORMATION IN ADOLESCENT GIRLS

机译：预测青少年多囊卵巢综合征形成的危险度的方法

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FIELD: medicine.;SUBSTANCE: invention can be used to predict the risk of polycystic ovarian syndrome (PCOS) formation in adolescent girls. As anamnestic data assess the presence of: hereditary burden on PCOS by both mother and father, burdened family history of type 2 diabetes, burdened heredity for obesity are estimated. The presence of each attribute is scored as 2 points. Also the presence of low ≤2800 g or high ≥4000 g body weight of the child at birth at mature gestation term, maternal gestational diabetes during pregnancy, excess of the mother's body weight during pregnancy, chronic tonsilogenous infections and frequent sore throats, traumatic brain injury, history of neuroinfection, sedentary lifestyle, severe psychoemotional stress in the girl are determined. If present, the attributes are scored as 1 point each. Among the clinical data the presence of: menstrual irregularities in the type of oligo-/amenorrhea for more than 1.5-2 years after menarche, anovulatory cycle, obesity - body mass index (BMI) more than 30 kg/m², hirsutism is estimated. The presence of each attribute is scored as 3 points. If there is an excess of body weight with a BMI of 26-30 kg/m², abdominal redistribution of fat deposits, borderline hairiness - 8-14 points on the Ferriman-Gallwey scale, increased greasiness of hair and skin, acne, seborrhea, negroid acanthosis, fibrocystic mastopathy, 2 points are assigned to each feature. 1 point is assigned to the presence of normal body weight, dysfunctional uterine bleeding in the puberty period. Laboratory indicators are identified: in the presence of an increase in the ratio of luteinizing hormone to follicle stimulating hormone (LH/FSH) of more than 2.5, 3 points are assigned. Also, the presence of an elevated level of luteinizing hormone, an increased level of total testosterone, an elevated level of androstenedione, an increase in insulin with an empty stomach, an increased level of glycosylated hemoglobin are also determined. If present, each indicator is scored as 2 points. If there is an increase in the anti-Mullerian hormone level above the age limit, 1 point is assigned. The echographic signs are determined: ovaries volume is more than 10 cm³, at least 12 cystic-atreducing follicles with a diameter of 2-9 mm, the presence of which is scored as 3 points. In the presence of multifollicular ovaries 1 point is assigned. The derived points are summed up. With a score of 1-15, low risk of polycystic ovary syndrome formation is indicated. The total score of 31-54 points shows a moderate degree of risk. The total score of 32-62 points - a high degree of risk of polycystic ovarian syndrome formation.;EFFECT: method allows to predict polycystic ovarian syndrome formation in adolescent girls objectively, effectively, simply and at an early stage by evaluating the complex of the most significant indicators.;1 tbl, 2 ex

机译：技术领域：发明内容：本发明可以用于预测青春期多囊卵巢综合征（PCOS）形成的风险。回忆数据评估了以下情况的存在：估计父母双方对PCOS的遗传负担，2型糖尿病的家族病史负担，肥胖的遗传病负担被估计。每个属性的存在得分为2分。在成熟妊娠期出生时，儿童体重低≤2800g或高≥4000g，孕期孕产妇妊娠糖尿病，孕期母亲体重超标，慢性扁桃体感染和咽喉痛，脑外伤确定女孩的伤害，神经感染史，久坐的生活方式，严重的心理情绪压力。如果存在，则每个属性得分为1分。在临床数据中，存在以下情况：月经初潮后1.5至2年以上的少经/闭经型月经不调，无排卵周期，肥胖-体重指数（BMI）超过30 kg / m ^{2 < / Sup>，估计多毛症。每个属性的存在得分为3分。如果体重超标，BMI为26-30 kg / m ^{2 ，则腹部脂肪沉积会重新分布，边缘毛发-Ferriman-Gallwey评分为8-14分，增加了油腻感头发和皮肤，痤疮，皮脂溢，坏死性棘皮病，纤维囊性乳腺病，每个特征分为2点。在青春期，正常体重，失调性子宫出血的存在是1分。确定实验室指标：在黄体生成激素与促卵泡激素（LH / FSH）之比增加超过2.5的情况下，分配3分。此外，还确定了黄体生成素水平升高，总睾丸激素水平升高，雄烯二酮水平升高，空腹胰岛素增加，糖基化血红蛋白水平升高的存在。如果存在，则每个指标得分为2分。如果抗-Mullerian激素水平增加到超过年龄限制，则分配1分。确定回声征象：卵巢体积大于10 cm ^{3 ，至少12个直径2-9 mm的减少囊肿的卵泡，得分为3分。在多卵泡卵巢的情况下，分配1个点。得出的点相加。评分为1-15，表明形成多囊卵巢综合征的风险较低。总分31-54分显示中等程度的风险。总分32-62分-多囊卵巢综合征形成的高风险。效果：该方法可通过评估女性的复杂程度，客观，有效，简单且在早期阶段预测青春期多囊卵巢综合征的形成。最重要的指标。; 1 tbl，2前}}}

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公开/公告号RU2629720C1

专利类型
公开/公告日2017-08-31

原文格式PDF
申请/专利权人 GOSUDARSTVENNOE BYUDZHETNOE OBRAZOVATELNOE UCHREZHDENIE VYSSHEGO PROFESSIONALNOGO OBRAZOVANIYA KURSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET MINISTERSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII;
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申请/专利号RU20160122383
发明设计人 MEDVEDEVA IRINA NIKOLAEVNA;KHURASEVA ANNA BORISOVNA;SVYATCHENKO KSENIYA SERGEEVNA;POLONIKOV ALEKSEJ VALEREVICH;
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申请日2016-06-06
分类号A61B5/00;G01N33/48;
国家 RU
入库时间 2022-08-21 13:23:22

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