首页> 外国专利> CORRELATION BETWEEN LONG NON-CODING RNA H19 AND CANCER PLATINUM-BASED CHEMOTHERAPEUTIC DRUG RESISTANCE

CORRELATION BETWEEN LONG NON-CODING RNA H19 AND CANCER PLATINUM-BASED CHEMOTHERAPEUTIC DRUG RESISTANCE

机译:长非编码RNA H19与基于癌症的铂类化疗药物耐药性的相关性

摘要

Provided are uses of an agent capable of reducing and/or inhibiting the expression of long non-coding RNA H19 in cancer cells in the preparation of a medicine for treating or preventing cancers, and in the preparation of a medicine for reducing the resistance of cancers to the platinum-based chemotherapeutic drug. Also provided is a use of an agent capable of detecting the expression of a long non-coding RNA H19 in the preparation of a test kit, the test kit being used for diagnosing the occurrence of cancers or predicting a cancer relapse, and for predicting, detecting or diagnosing the resistance to the platinum-based chemotherapeutic drug of a cancer patient.
机译:提供了能够减少和/或抑制癌细胞中长非编码RNA H19表达的试剂在制备用于治疗或预防癌症的药物中以及在制备用于降低癌症抵抗力的药物中的用途。铂类化学治疗药物。还提供了能够检测长的非编码RNA H19表达的试剂在制备测试试剂盒中的用途,该测试试剂盒用于诊断癌症的发生或预测癌症的复发,以及用于预测,检测或诊断癌症患者对铂类化学治疗药物的耐药性。

著录项

  • 公开/公告号WO2017031993A1

    专利类型

  • 公开/公告日2017-03-02

    原文格式PDF

  • 申请/专利权人 ZHEJIANG UNIVERSITY;

    申请/专利号WO2016CN79538

  • 发明设计人 HUA YUEJIN;ZHENG ZHIGUO;XU HONG;

    申请日2016-04-18

  • 分类号A61K48;A61K31/7088;A61P35;C12Q1/68;C12N15/113;

  • 国家 WO

  • 入库时间 2022-08-21 13:31:59

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