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AN ASSAY FOR EVALUATION OF BIOMOLECULE TRANSFER AND UPTAKE BY KERATINOCYTE CELLS
AN ASSAY FOR EVALUATION OF BIOMOLECULE TRANSFER AND UPTAKE BY KERATINOCYTE CELLS
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机译:角质化细胞对生物分子转移和摄取的评价研究。
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摘要
The present invention relates generally to a high throughput in-vitro assay for testing a compound for its tendency to promote or inhibit the transfer of melanin, between cell(s). The in-vitro assay/method also allows testing the extent of a biomolecule uptake or transfer, preferably melanin, in a cell or from a cell. The invention further provides a kit for performing the above mentioned in-vitro assay. The present assay and the kit possesses the technical advantageous property of being efficient in reducing the total assay time, having high throughput and generating minimum background noise while evaluating the uptake/transfer of melanin between melanocyte and Keratinocyte.
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