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Meningococcal multivalent native outer membrane vesicle vaccine, methods of manufacture and use thereof

机译:脑膜炎球菌多价天然外膜囊泡疫苗,其制备方法和用途

摘要

The present technology provides vaccine compositions comprising native outer membrane vesicles (NOMVs) from at least one genetically modified strain of Neisseria which provides protective immunity to meningococcal disease, more preferably subtype B meningococcal disease. The present technology further provides methods of immunizing an animal or human against meningococcal disease comprising administering the vaccine composition of the present invention.
机译:本技术提供了疫苗组合物,其包含来自至少一种基因改造的奈瑟氏球菌的天然外膜囊泡(NOMV),其提供了针对脑膜炎球菌疾病,更优选为B型脑膜炎球菌疾病的保护性免疫。本技术进一步提供了免疫动物或人以抵抗脑膜炎球菌疾病的方法,其包括施用本发明的疫苗组合物。

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