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TEMPORAL PEDIATRIC SEPSIS BIOMARKER RISK MODEL

机译:暂时性小儿脓毒症生物标志物风险模型

摘要

Methods and compositions disclosed herein generally relate to methods of identifying, validating, and measuring clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses for blood, vascular, cardiac, and respiratory tract dysfunction, particularly as those responses relate to septic shock in pediatric patients. In particular, the invention relates to identifying one or more biomarkers associated with septic shock in pediatric patients, obtaining a sample from a pediatric patient having at least one indication of septic shock, then quantifying from the sample an amount of one or more of said biomarkers, wherein the level of said biomarker correlates with a predicted outcome.
机译:本文公开的方法和组合物总体上涉及鉴定,验证和测量针对血液,血管,心脏和呼吸道功能障碍的诊断和治疗反应的临床相关的,可量化的生物标志物的方法,尤其是那些反应与小儿患者的败血性休克有关。特别地,本发明涉及在儿科患者中鉴定与败血性休克相关的一种或多种生物标志物,从儿科患者获得具有至少一种败血性休克适应症的样品,然后从样品中定量一种或多种所述生物标志物的量。 ,其中所述生物标志物的水平与预测结果相关。

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