首页> 外国专利> PLASTID-EXPRESSED MYCOBACTERIUM TUBERCULOSIS VACCINE ANTIGENS ESAT-6 AND MTB72F FUSED TO CHOLERA TOXIN B SUBUNIT

PLASTID-EXPRESSED MYCOBACTERIUM TUBERCULOSIS VACCINE ANTIGENS ESAT-6 AND MTB72F FUSED TO CHOLERA TOXIN B SUBUNIT

机译：质体表达结核分枝杆菌结核分枝杆菌疫苗抗原ESAT-6和MTB72F融合至霍乱毒素B亚单位

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摘要

Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is one of the leading reasons for death by an infectious bacterial pathogen. Disclosed herein are compositions and methods of using same related to chloroplast expressed TB antigens. Also disclosed is the bioencapsulation of the TB antigens that enables the oral administration of the composition while preserving immunizing efficacy.

机译：结核（TB）是由结核分枝杆菌引起的，并且是传染性细菌病原体导致死亡的主要原因之一。本文公开了与叶绿体表达的TB抗原有关的组合物和使用它们的方法。还公开了TB抗原的生物包封，其使得能够口服施用该组合物，同时保持免疫效力。 展开▼

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公开/公告号US2015196627A1

专利类型

公开/公告日2015-07-16

原文格式PDF

申请/专利权人 UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION INC.;
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申请/专利号US201214353998

发明设计人 HENRY DANIELL;
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申请日2012-10-24

分类号A61K39/04;C07K14/35;

国家 US

入库时间 2022-08-21 15:26:31

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1. 可表达结核分枝杆菌Ag85B和ESAT-6融合蛋白的重组耻垢分枝杆菌株及其应用 [P] . 中国专利： CN101875913B . 2012.05.23

2. 可表达结核分枝杆菌Ag85B和ESAT-6融合蛋白的重组耻垢分枝杆菌株及其应用 [P] . 中国专利： CN101875913A . 2010-11-03

3. PLASTID-EXPRESSED MYCOBACTERIUM TUBERCULOSIS VACCINE ANTIGENS ESAT-6 AND MTB72F FUSED TO CHOLERA TOXIN B SUBUNIT [P] . 欧洲知识产权局专利： EP2771469A4 . 2015-04-08

机译：质体表达结核分枝杆菌结核分枝杆菌疫苗抗原ESAT-6和MTB72F融合至霍乱毒素B亚单位

4. PLASTID-EXPRESSED MYCOBACTERIUM TUBERCULOSIS VACCINE ANTIGENS ESAT-6 AND MTB72F FUSED TO CHOLERA TOXIN B SUBUNIT [P] . 欧洲知识产权局专利： EP2771469A1 . 2014-09-03

机译：质体表达结核分枝杆菌结核分枝杆菌疫苗抗原ESAT-6和MTB72F融合至霍乱毒素B亚单位

5. PLASTID-EXPRESSED MYCOBACTERIUM TUBERCULOSIS VACCINE ANTIGENS ESAT-6 AND MTB72F FUSED TO CHOLERA TOXIN B SUBUNIT [P] . 世界知识产权组织专利： WO2013063059A1 . 2013-05-02

机译：质体表达结核分枝杆菌结核分枝杆菌疫苗抗原ESAT-6和MTB72F融合至霍乱毒素B亚单位

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