首页> 外国专利> Modifying glycosylation profile of a glycosylation site contained in a target peptide, comprises recombinantly producing a fusion protein made of a mint protein and the target peptide, which contains predetermined glycosylation site

Modifying glycosylation profile of a glycosylation site contained in a target peptide, comprises recombinantly producing a fusion protein made of a mint protein and the target peptide, which contains predetermined glycosylation site

机译:修饰靶标肽中包含的糖基化位点的糖基化分布包括重组产生由薄荷蛋白和靶标肽组成的融合蛋白,所述融合蛋白包含预定的糖基化位点

摘要

Modifying glycosylation profile of a glycosylation site contained in a target peptide, comprises recombinantly producing a fusion protein made of a mint protein and the target peptide, which contains predetermined glycosylation site, where the mint protein is a glycoprotein with at least one glycosylation site contained in the glycoprotein, and the target peptide receives the glycosylation profile of the mint protein during the recombinant production of the predetermined glycosylation site. An independent claim is included for the fusion protein and/or glycosylated target peptide obtained by the method.
机译:改变靶标肽中包含的糖基化位点的糖基化分布的方法包括重组生产由薄荷蛋白和目标肽组成的融合蛋白,所述融合蛋白包含预定的糖基化位点,其中所述薄荷蛋白是具有至少一个糖基化位点的糖蛋白。糖蛋白,并且在预定糖基化位点的重组生产过程中,靶肽接受薄​​荷蛋白的糖基化谱。对于通过该方法获得的融合蛋白和/或糖基化靶标肽包括独立权利要求。

著录项

  • 公开/公告号DE102012105416A1

    专利类型

  • 公开/公告日2013-12-24

    原文格式PDF

  • 申请/专利权人 CHARITE - UNIVERSITAETSMEDIZIN BERLIN;

    申请/专利号DE201210105416

  • 发明设计人 BERGER MARKUS;KAUP MATTHIAS;

    申请日2012-06-21

  • 分类号C07K14/435;C12N1/00;

  • 国家 DE

  • 入库时间 2022-08-21 15:37:51

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