首页> 外国专利> GENERATION OF VIRUS-LIKE PARTICLES AND DEMONSTRATION OF LIPID RAFTS AS SITES OF FILOVIRUS ENTRY AND BUDDING

GENERATION OF VIRUS-LIKE PARTICLES AND DEMONSTRATION OF LIPID RAFTS AS SITES OF FILOVIRUS ENTRY AND BUDDING

机译:类病毒颗粒的产生和脂筏的花丝进入和融合的论证

摘要

In this application is described a method for the formation of filovirus-like particles for both Ebola and Marburg and their use as a diagnostic and therapeutic agent as well as a filovirus vaccine. Also described is the association of Ebola and Marburg with lipid rafts during assembly and budding, and the requirement of functional rafts for entry of filoviruses into cells.
机译:在本申请中描述了形成埃博拉和马尔堡丝状病毒样颗粒的方法,以及它们用作诊断和治疗剂以及丝状病毒疫苗的用途。还描述了埃博拉病毒和马尔堡病毒在组装和萌芽期间与脂质筏的关系,以及功能性筏对丝状病毒进入细胞的要求。

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