首页> 外国专利> GENERATION OF VIRUS-LIKE PARTICLES AND DEMONSTRATION OF LIPID RAFTS AS SITES OF FILOVIRUS ENTRY AND BUDDING

GENERATION OF VIRUS-LIKE PARTICLES AND DEMONSTRATION OF LIPID RAFTS AS SITES OF FILOVIRUS ENTRY AND BUDDING

机译：类病毒颗粒的产生和脂筏的花丝进入和融合的论证

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摘要

In this application is described a method for the formation of filovirus-likeparticles for both Ebola and Marburg and their use as a diagnostic andtherapeutic agent as well as a filovirus vaccine. Also described is theassociation of Ebola and Marburg with lipid rafts during assembly and budding,and the requirement of functional rafts for entry of filoviruses into cells.

机译：在该申请中描述了形成丝状病毒样的方法用于埃博拉和马尔堡的颗粒及其在诊断和诊断中的用途治疗剂以及丝状病毒疫苗。还描述了组装和萌芽期间埃博拉病毒和马尔堡病毒与脂筏的关系，以及功能性木筏将丝状病毒进入细胞的要求。

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公开/公告号CA2465895C

专利类型
公开/公告日2012-10-02

原文格式PDF
申请/专利权人 U.S. ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES DEPARTMENT O F THE ARMY;
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申请/专利号CA20022465895
发明设计人 SCHMALJOHN ALAN L.;AMAN M. JAVAD;BAVARI SINA;
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申请日2002-11-07
分类号C12N7/01;A61K31/335;A61K31/365;A61K31/7048;A61K31/724;A61K39/12;C07K14/08;C12N7/04;C12N15/40;C12Q1/70;
国家 CA
入库时间 2022-08-21 17:20:54

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