首页> 外国专利> ISOLATED HUMAN AUTOANTIBODIES TO NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (NGAL) AND METHODS AND KITS FOR THE DETECTION OF HUMAN AUTOANTIBODIES TO NGAL

ISOLATED HUMAN AUTOANTIBODIES TO NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (NGAL) AND METHODS AND KITS FOR THE DETECTION OF HUMAN AUTOANTIBODIES TO NGAL

机译:中性核糖核酸酶相关脂蛋白(NGAL)的分离人自身抗体以及将人自身抗体检测为NGAL的方法和试剂盒

摘要

A method of determining the presence, amount or concentration of at least one autoantibody that reacts with neutrophil gelatinase-associated lipocalin (NGAL), alone or in further combination with a method of determining the concentration of NGAL, which methods can further comprise diagnosing, prognosticating, or assessing the efficacy of a therapeutic/prophylactic treatment of a patient and, optionally, modifying the therapeutic/prophylactic treatment of the patient as needed to improve efficacy; a kit comprising at least one component for assaying a test sample for at least one autoantibody that reacts with NGAL and instructions for assaying; a method of isolating an autoantibody that reacts with NGAL; an isolated autoantibody that reacts with NGAL; and a method for determining the reliability of an NGAL assay result.
机译:一种确定至少一种与嗜中性白细胞明胶酶相关脂钙蛋白(NGAL)反应的自身抗体的存在,数量或浓度的方法,该方法可以单独或与确定NGAL浓度的方法进一步组合使用,该方法可以进一步包括诊断,预后,或评估患者的治疗/预防性治疗的功效,并视需要修改患者的治疗/预防性治疗以提高疗效;试剂盒,其包含至少一种用于测定测试样品中至少一种与NGAL反应的自身抗体的成分以及用于测定的说明书;分离与NGAL反应的自身抗体的方法;与NGAL反应的分离的自身抗体;以及用于确定NGAL测定结果的可靠性的方法。

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