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Variation in the CHI3L1 Gene Influences Serum YKL-40 Levels, Asthma Risk and Lung Function
Variation in the CHI3L1 Gene Influences Serum YKL-40 Levels, Asthma Risk and Lung Function
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机译：CHI3L1基因的变异影响血清YKL-40水平，哮喘风险和肺功能
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摘要
The present invention is based on the discovery that a single nucleotide polymorphism (SNP) present the chitinase 3-like 1 gene (CHI3L1) encoding YKL-40 or a regulatory domain of the CHI3L1 gene, is associated with elevated YKL-40 levels, as well as an increased risk for developing a lung disorder, including asthma, bronchial hyperresponsivity, and/or reduced lung function.
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