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SUSTAINED-RELEASE CARRIER, DRUG USING THE SUSTAINED-RELEASE CARRIER AND DRUG DELIVERY SYSTEM USING THE DRUG
SUSTAINED-RELEASE CARRIER, DRUG USING THE SUSTAINED-RELEASE CARRIER AND DRUG DELIVERY SYSTEM USING THE DRUG
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机译：持续释放载体，使用药物的持续释放载体和药物输送系统
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摘要
PROBLEM TO BE SOLVED: To provide a sustained-release carrier that is derived from a naturally occurring substance, has a film-forming property and exerts excellent water retention even in the presence of a salt, a drug using the sustained-release carrier, and a drug delivery system using the drug.;SOLUTION: The sustained-release carrier is prepared by dissolving sacran derived from Aphanothece sacrum in water or a solvent containing water, and adding a trivalent cation to the resulting solution so as to form gel. The drug can be carried by the resulting gel. The drug is prepared using the sustained-release carrier. In the drug delivery system, the amount of the drug released can be adjusted by first administering the drug to a living body and subsequently administering a preparation containing a chelating agent, a trivalent cation or an enzyme that cleaves a sugar chain in sacran so as to act on the sacran gel.;COPYRIGHT: (C)2011,JPO&INPIT
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